Fully Funded PhD Positions in Structural Biology, Cryo-EM, Antimicrobial Resistance and Virology University of Leicester in United Kingdom

Funded PhD opportunity in viral DNA mimic proteins at the University of Bristol. Professor Mark Dillingham is seeking an enthusiastic PhD student to investigate how bacterial viruses (phages) produce proteins that masquerade as DNA and sabotage molecular machinery in bacterial hosts. The project will focus on discovering new DNA mimic proteins and understanding their mechanisms, including viral targeting of the bacterial DNA-processing enzyme RecBCD. Research will combine computational structura...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...

PhD opportunity at the University of East Anglia in rewiring photosynthetic pathways in a purple bacterium , hosted by the School of Biological Sciences and supervised by Professor Tom Clarke . This project focuses on biochemistry , biotechnology , microbiology , molecular biology , and structural biology . The research aims to engineer Rhodopseudomonas palustris so that light-driven iron oxidation and DMSO respiration can operate together, enabling light-driven iron and DMSO reduction while byp...

PhD opportunity in DNA repair at stalled replication forks at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom . The project focuses on DNA repair , replication stress , and the Fanconi Anaemia (FA) pathway , with particular attention to how cells respond to DNA crosslinks and stalled replication forks. The research aims to understand the molecular mechanisms of crosslink repair and the role of the FANCD2-FANCI heterodimer and FA core complex in mai...

PhD opportunity at the John Innes Centre in Norwich, United Kingdom, in the laboratory of Prof. Tung Le within the Department of Molecular Microbiology. The project, titled “Breaking Code: Deciphering the Biology of the Selfless Virus-like Gene Transfer Agents” , focuses on horizontal gene transfer , gene transfer agents (GTAs) , bacterial domestication of viral elements, and the biology of DNA exchange in bacteria. The research is highly relevant to understanding how genetic information is diss...