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CP2M Laboratory (CNRS/UCBL/CPE Lyon)

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Master's Internship in Molecular Dynamics Simulation of Lipid Nanoparticles CP2M Laboratory (CNRS/UCBL/CPE Lyon) in France

Degree Level

Master's

Field of study

Computer Science

Funding

Master's internship for 6 months with a net monthly salary of €600.

Deadline

Feb 28, 2027

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Country

France

University

CP2M Laboratory (CNRS/UCBL/CPE Lyon)

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Keywords

Computer Science
Chemistry
Biomedical Engineering
Materials Science
Biology
Molecular Dynamics
Polymer Chemistry
Rna Biology
Lipid Nanoparticles
Macromolecular Science
Physics

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About this position

Master's internship opportunity in molecular dynamics simulation of lipid nanoparticles (LNPs) at the CP2M Laboratory (UMR 5128, UCBL–CNRS) in Villeurbanne, France. The project sits at the intersection of chemistry, materials science, biophysics, and computational modeling, with a strong focus on the physical chemistry of polymers, colloids, lipids, and RNA.

The internship is part of the LIONS project, funded by Bpifrance and the Auvergne–Rhône-Alpes Region, in partnership with Xenocs and Dillico. The student will work on understanding the internal structure of LNPs used for nucleic acid delivery, combining SAXS experiments with coarse-grained molecular dynamics simulations, especially using the MARTINI force field.

Research tasks include parameterizing ionizable lipids and RNA, measuring membrane thickness and scattering length density profiles, analyzing lipid membrane–RNA interactions via umbrella sampling, and assessing membrane rigidity through lipid pulling and fluctuation analysis.

Eligibility: Master 2 students in polymer chemistry, macromolecular chemistry, materials chemistry, or a related field. Helpful skills include Linux, bash, Python, basic MD knowledge, and experience with GROMACS. A background in soft-matter physical chemistry and biomolecular systems is desirable, along with strong problem-solving and communication skills.

Duration is 6 months with a net monthly salary of €600. The application deadline shown is 2027-02-28, and the position is to start as soon as possible.

Funding details

Master's internship for 6 months with a net monthly salary of €600.

What's required

Master's Year 2 degree in Polymer Chemistry, Macromolecular Chemistry, Materials Chemistry, or a related field. Desired skills include proficiency in Linux, bash, and Python or similar for data analysis, basic knowledge of molecular dynamics, experience with simulation software such as GROMACS, understanding of soft-matter physical chemistry (lipid membranes, RNA, biomolecular systems), and strong problem-solving, communication skills, and curiosity for interdisciplinary research.

How to apply

Check the ABG application page and use the site's application process to submit your candidacy. The post does not provide a direct email or form link in the text shown.

More information can be found here

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