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Ahmed Ghallab

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PhD candidate (f/m/d) for the Department of Toxicology Leibniz Research Centre for Working Environment and Human Factors (IfADo) in Germany

Degree Level

PhD

Field of study

Biochemistry

Funding

65% part-time PhD position for 36 months; remuneration according to EG 13 TV-L, from EUR 3,093.59 to EUR 4,397.05 per month depending on qualifications, plus public-sector benefits.

Deadline

Nov 30, 2026

Country flag

Country

Germany

University

IfADo – Leibniz Research Centre for Working Environment and Human Factors

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Keywords

Biochemistry
Molecular Biology
Biology
Toxicology
Gene Expression
Hepatology
Immunohistochemistry
Medical Science
Pharmacy
Mouse Model
Clinicopathology

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About this position

Leibniz Research Centre for Working Environment and Human Factors (IfADo) in Dortmund is offering a PhD position in the Department of Toxicology within an interdisciplinary research environment that combines ergonomics, immunology, toxicology, psychology, and neuroscience.

The project focuses on metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression from steatosis to steatohepatitis and more severe liver disease. The research aims to clarify how bile macropinocytosis contributes to disease progression, and to identify mechanisms that could be targeted to slow or prevent the worsening of liver injury.

The doctoral researcher will work on an in vivo project using mouse models of MASLD progression. The work includes preparing and characterizing mouse models, carrying out therapeutic intervention experiments, collecting tissue and blood samples, and processing biological material for downstream analysis. The project also involves histopathological and immunohistochemical examination of liver tissue, biochemical analysis of blood samples, and gene expression studies. In addition, the candidate will contribute to data analysis and present findings in departmental seminars.

The research uses modern methods and infrastructure, including functional intravital imaging, ELISA, real-time quantitative PCR, and immunoblotting. The advertised position is embedded in a research program supported by the Deutsche Forschungsgemeinschaft (DFG), and the department highlights access to well-equipped cell and molecular biology laboratories, confocal and two-photon microscopy, and a mouse facility with reporter strains for liver cell types.

Prof. Ahmed Ghallab is listed as the contact person for this opportunity.

Funding details

65% part-time PhD position for 36 months; remuneration according to EG 13 TV-L, from EUR 3,093.59 to EUR 4,397.05 per month depending on qualifications, plus public-sector benefits.

What's required

Master's degree or diploma/state examination in biology, biochemistry, biotechnology, pharmacy, toxicology, medicine, or a related field with an excellent final grade. Applicants should be willing to perform animal experiments and learn microintervention techniques including different routes of drug administration, microsurgery, and biological sample collection. Basic knowledge of molecular biology techniques is required, along with the ability to work independently and responsibly as well as in a team. Interest in learning and establishing new techniques/technologies, presenting data at international conferences, proficiency in spoken and written English, and an aspiration to pursue a research/academic career are expected.

How to apply

Prepare a single PDF with your CV, motivation letter, university graduation certificates, and two references. Include the reference code FB Toxi 06/26 and submit by email to [email protected]. Direct questions to Prof. Ahmed Ghallab at [email protected].

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Professors

Prof. at Leibniz Research Centre for Working Environment and Human Factors (IfADo)

University Name
Country flag

Germany

Research Interests

Pharmacy

Biochemistry

Biology

Clinicopathology

Gene Expression