Bregje Wertheim
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PhD: How taste is encoded in the brain of caterpillars & butterflies Wageningen University & Research in Netherlands
Degree Level
PhD
Field of study
Molecular Biology
Funding
Fully funded PhD position; gross salary €3,204 per month in the first year rising to €4,051 per month in the fourth year (CAO-NU scale P); 38 hours per week; temporary contract for 18 months, extendable for the project duration if performance is good.
Deadline
Nov 29, 2026
Country
Netherlands
University
Wageningen University & Research
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About this position
This PhD project at Wageningen University & Research investigates how taste is encoded in the brain of specialist caterpillars and butterflies. The work focuses on deciphering the neuronal code that these insects use to recognize their host plants, using the cabbage white butterflies (Pieris spp.) as a model system.
The project sits at the intersection of neuroscience, ecology, and evolutionary biology. It explores how insect herbivores and plants have coevolved, how toxic plant compounds and insect defenses shape feeding and egg-laying behavior, and why closely related species or life stages can respond differently to the same plant chemicals. A particular comparative angle comes from species such as Pieris napi, which differs from other Pieris species in its oviposition behavior on cardenolide-containing plants.
Methodologically, the PhD candidate will study taste processing in the butterfly and caterpillar brain using intra- and extracellular electrophysiological recordings, visualization of neuronal networks by confocal microscopy and computer reconstruction, and the generation and maintenance of transgenic insect lines. The project also uses CRISPR/Cas9-mutant butterflies to test how loss of key receptor genes alters host-plant encoding in the brain.
The research is embedded in the Laboratory of Entomology at Wageningen University & Research and is part of the PE&RC graduate school, offering an international research setting and access to training opportunities. The position is supervised by Prof. Bregje Wertheim and co-supervised by Dr. Alexander Haverkamp. The advertised duties also include supporting teaching and mentoring activities through supervision of MSc and BSc students and assistance with lab practicals.
Together, the project aims to provide insight into the neuronal mechanisms underlying insect-plant coevolution and sensory ecology.
Funding details
Fully funded PhD position; gross salary €3,204 per month in the first year rising to €4,051 per month in the fourth year (CAO-NU scale P); 38 hours per week; temporary contract for 18 months, extendable for the project duration if performance is good.
What's required
A completed MSc degree or equivalent in Biology, Neurobiology or a related field is required. The candidate should be a creative and proactive team player with a strong interest in insect sensory ecology and the coevolution of insects and plants, and be willing to work across neurobiology, molecular biology and chemical ecology. An affinity for butterflies and caterpillars, ideally with a background in plant-insect interactions, is preferred. Experience with electrophysiology, especially in the insect brain, is desirable, and knowledge of molecular techniques and analytic chemistry is an advantage. Excellent communication skills in English and experience in scientific writing are required. English proficiency at C1 level is expected, and an internationally recognised certificate of proficiency may sometimes be required.
How to apply
Apply via the AcademicTransfer application link. Prepare your application materials in line with the vacancy and submit before the deadline. If you have questions, contact the recruiters at Wageningen University & Research.
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Professors
Prof. at Wageningen University & Research
Netherlands
Research Interests
Entomology
Neuropsychology
Biology
Molecular Biology
Environmental Science
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.