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University of Southampton

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PhD in AI-Guided Phage Engineering for Clinical Care in Military Operations University of Southampton in United Kingdom

Degree Level

PhD

Field of study

Computer Science

Funding

The project is competition funded. Specific stipend, tuition-fee coverage and other financial details are not stated in the supplied text; applicants should consult the University of Southampton fees and funding information.

Deadline

Dec 18, 2026

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Country

United Kingdom

University

University of Southampton

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Keywords

Computer Science
Epidemiology
Microbiology
Biomedical Engineering
Biology
Synthetic Biology
Antibiotic Resistance
Medical Science
Bacterial Genomic

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About this position

This Doctor of Philosophy project at the University of Southampton will develop AI-guided synthetic bacteriophages for clinical care in military and conflict-related healthcare settings.

The research addresses antimicrobial resistance and multidrug-resistant organisms, including Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacterales and Staphylococcus aureus. The project will investigate bacterial diversity and genomic characteristics in challenging healthcare environments and explore phages as targeted alternatives to antibiotics.

You will combine environmental surveillance and bacterial genomics with AI-assisted phage design, genome synthesis and experimental phage susceptibility testing. The work will establish an iterative design–build–test–learn platform, using experimentally characterised phages to improve computational models and generate phages tailored to clinically important drug-resistant bacteria.

The project provides interdisciplinary research training across epidemiology, artificial intelligence, comparative genomics, synthetic biology, phage biology and laboratory microbiology. The research environment spans academic and government partners including the military, the University of Southampton, the University of Oxford, the UK Health Security Agency and the Defence Science and Technology Laboratory, with biotechnology expertise from New England Biolabs. It also includes two three-month placements at New England Biolabs headquarters in Massachusetts, USA.

This competition-funded PhD is based at the University of Southampton and has a closing date of 18 December 2026.

Funding details

The project is competition funded. Specific stipend, tuition-fee coverage and other financial details are not stated in the supplied text; applicants should consult the University of Southampton fees and funding information.

What's required

Applicants require a 2:1 honours degree. The project calls for interdisciplinary interest or preparation spanning AI, genomics, synthetic biology, phage biology, microbiology and antimicrobial resistance; full entry requirements should be checked on the University of Southampton project page.

How to apply

Review the full project, entry requirements and fees-and-funding information on the University of Southampton page. Apply through the university's postgraduate research application process before 18 December 2026.

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