PhD in Biochemistry and Structural Biology: Non-canonical Proteolytic Activity of Deubiquitinating Enzymes University of Dundee in United Kingdom

PhD opportunity at the University of Bath in peptide design, TFEB activation, autophagy, lysosome biology, neurodegeneration, biochemistry, biophysics, cell biology, molecular biology, structural biology, and neuroscience . This project is part of the GW4 BioMed3 MRC Doctoral Landscape Programme (DLP) , which offers up to 17 studentships for entry in September 2026 . The project asks whether designed peptides can directly activate TFEB , a key regulator of cellular waste clearance, to improve re...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in structural biology, virology, biochemistry, biophysics, and molecular biology . This funded PhD project, supervised by Dr I Taylor , focuses on the ZAP antiviral response and how the proteins ZAP, KHNYN, and Trim25 assemble into molecular complexes that recognize viral RNA and trigger RNA degradation. The project aims to uncover the structure and mechanism of this antiviral system using protein purification, RNA-binding as...

PhD opportunity at the University of St Andrews in the School of Biology: EastBIO: Understanding human sulfatases involved in heparan sulfate degradation . This project sits at the intersection of biochemistry , molecular biology , structural biology , biophysics , and biomedical engineering . The research focuses on human lysosomal sulfatases that act on heparan sulfate, with the goal of understanding their structure, mechanism, function, and disease relevance . The work connects directly to ly...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences with Dr Maisem Laabei on targeted covalent macrocycles for immune-mediated diseases . The project focuses on the complement system and pathway-specific inhibition of key serine proteases, especially C1s and factor D , to develop more selective therapies for inflammatory and autoimmune conditions. Research themes include biochemistry , molecular biology , microbiology , phage display , chemical s...

PhD opportunity in Structure-Function Analysis of Stress Signaling at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with supervision by Dr A Bertolotti. The lab studies stress signaling and the integrated stress response (ISR), with a strong focus on how cells protect themselves from misfolded proteins and how these pathways may be harnessed to improve resilience in disease. The project is especially relevant to neurodegenerative diseases such as Alzheimer’s disease,...