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Oliver Seitz

4 days ago

PhD in Bioorganic Chemistry: Chemical Synthesis of Peptide-DNA/PNA Conjugates and Cell Assays Humboldt-Universität zu Berlin in Germany

Degree Level

PhD

Field of study

Chemistry

Funding

Available

Deadline

Dec 16, 2026

Country flag

Country

Germany

University

Humboldt-Universität zu Berlin

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Keywords

Chemistry
Organic Chemistry
Biology
Peptide Chemistry
Microscopy
Chemical Biology
Nucleic Acid Chemistry

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About this position

Humboldt-Universität zu Berlin is offering a PhD project in the Department of Chemistry at the Faculty of Mathematics and Natural Sciences, supervised by Prof. Dr. Oliver Seitz. The position is embedded in bioorganic synthesis at the chemistry/biochemistry interface and focuses on the chemical construction of peptide-DNA and peptide-PNA conjugates.

The doctoral researcher will work on the synthesis and biological evaluation of these conjugates, combining organic synthesis with analytical and bioanalytical workflows. The project includes solid-phase peptide synthesis, conjugation chemistry, fluorescence labelling, HPLC purification, and bioassays. A further focus is the sequence-programmed assembly of nanostructures and their investigation through cell-based experiments.

The research environment connects synthetic chemistry with biological readouts such as fluorescence microscopy and flow cytometry. The role includes scientific services in research and teaching, as well as tasks contributing to the candidate’s own doctoral qualification.

Funding details

Available

What's required

Completed university degree in (bio)organic chemistry (Diploma, Master or equivalent), preferably with very good results; theoretical and practical experience in peptide chemistry and nucleic acid chemistry is beneficial; knowledge of cellular bioassays and experience in fluorescence spectroscopy/imaging are desired; applicants should be open to interdisciplinary natural sciences research, highly motivated for independent scientific work, and have very good communication, teamwork, and written/spoken English skills.

How to apply

Send a single PDF application including statement of purpose, CV, relevant certificates, and a contact person for reference. Quote reference number DR/177/26. Apply by email to [email protected] or follow the university job page for the legally binding German description.

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Professors

Prof. Dr. at Humboldt-Universität zu Berlin

University Name
Country flag

Germany

Research Interests

Organic Chemistry

Chemical Biology

Chemistry

Microscopy

Biology