PhD in Genetic Mechanisms of Metabolic Rate Control in Birds and Mammals The Francis Crick Institute in United Kingdom

Funded PhD opportunity at the MRC Laboratory of Medical Sciences (LMS) in London, United Kingdom, on spatial and three-dimensional genome regulation during zygotic genome activation (ZGA) . This project explores how chromatin architecture, promoter-enhancer communication, boundary formation, insulation, and spatially restricted transcriptional states are coordinated as the embryonic genome becomes active. The work sits at the intersection of developmental genomics , chromatin biology , genomics ...

PhD opportunity at the University of St Andrews in the School of Biology on FoxP2, vocal learning, speech and language evolution, transgenic bats, molecular genetics, neuroscience, bioinformatics . This EASTBIO/BBSRC-funded 4-year PhD project investigates how humans evolved speech and language by studying vocal learning in bats, a rare mammalian model for complex communication. The project focuses on the molecular and neural mechanisms of vocal learning, including the role of FoxP2 , a gene impl...

PhD opportunity at the University of Cambridge / Cancer Research UK Cambridge Institute in tumour-initiating states , cancer biology , cell biology , genetics , genomics , molecular biology , molecular genetics , and related bioinformatics / epigenetics approaches. The project, supervised by Prof Masashi Narita , focuses on the biology of preneoplastic cell states and how cell identity, plasticity, chromatin organisation, and gene regulation are reshaped by oncogenic and metabolic signalling. Th...

Funded PhD project at The Francis Crick Institute with Dr George Kassiotis on evolution of novel function through retrotransposable element exaptation . The project sits at the intersection of genetics , genomics , bioinformatics , evolution , immunology , and cancer biology , focusing on how transposable elements (TEs) and retrotransposable elements (RTEs) are co-opted to create new gene functions, alternative isoforms, and disease-relevant regulatory changes. The research background highlights...

PhD opportunity at the University of Oxford in the Department of Paediatrics on developing a precision RNA editing platform for therapeutic applications . This funded DPhil project focuses on RNA editing , antisense oligonucleotides (ASOs) , genetics , genomics , molecular biology , molecular genetics , and cell biology . The project aims to identify disease-causing mutations amenable to RNA editing, engineer ASO conjugates that target endogenous RNA editors, and test lead candidates in reporter...