PhD in In Situ Structural Biology of Cellular Adaptation The Francis Crick Institute in United Kingdom

PhD opportunity at The Francis Crick Institute with Dr Peter Rosenthal on cryomicroscopy of lipid-enveloped virus entry and assembly . The project sits at the intersection of structural biology , virology , cell biology , and biophysics , with a strong emphasis on cryo-EM , cryo-ET , and related imaging/computational methods. The research aims to directly image key steps in infection by lipid-enveloped viruses such as influenza and retroviruses . Topics include virus entry, receptor binding, mem...

The Neginskaya Laboratory in the Department of Physiology and Cell Biology at The Ohio State University is recruiting a Postdoctoral Scholar to study the molecular mechanisms of mitochondrial permeability transition and mitochondrial dysfunction in disease. This position is centered on physiology , cell biology , biochemistry , biophysics , and structural biology , with projects examining mitochondrial membrane protein complexes, stress-induced permeability changes, and signaling pathways involv...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in regulatory switching of a microtubule motor-scaffold complex with Dr Sami Chaaban. This funded PhD project focuses on how microtubule motors , especially kinesins , organize microtubules and position regulatory proteins during cell division. The project asks how interactions with regulatory partners switch kinesins between functional states and how these changes shape specialized microtubule structures. Research methods in...

PhD opportunity at The Francis Crick Institute in London, United Kingdom: Enabling antibiotics discovery by targeted protein degradation with Dr Francesca Ester Morreale. This funded PhD project focuses on targeted protein degradation (TPD) in pathogenic bacteria as a new strategy for antibiotic discovery . The project will explore how to design novel antibiotic degraders and study their mechanism of action using biochemistry , biophysics , proteomics , and molecular microbiology . The lab’s bro...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...