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University of Southampton

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PhD in Metabolic Health and Fitness to Serve: GLP-1 Receptor Agonists on Pancreas–Bone Crosstalk University of Southampton in United Kingdom

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

Competition funded.

Deadline

Dec 18, 2026

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Country

United Kingdom

University

University of Southampton

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Keywords

Biomedical Engineering
Biology
Nutrition
Neuropsychology
Medical Science

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About this position

PhD opportunity at the University of Southampton on metabolic health, GLP-1 receptor agonists, and pancreas–bone crosstalk.

This project asks whether bone density loss seen in people taking GLP-1 weight-loss drugs is caused by the medication itself or by weight loss and reduced skeletal loading. It also investigates possible pancreatic effects of long-term exposure, especially in people with excess pancreatic fat.

You will work with micro-CT imaging of patient pancreatic tissue, human stem-cell derived pancreatic models, and patient-derived organoids. The project will test whether signals from drug-treated pancreatic tissue alter how bone cells build and break down bone. This is a strongly translational project with relevance to medical science, biology, and biomedical engineering, with clear implications for defence-related bone stress injury and physical training.

Funding: competition funded.

Entry requirements: a 2:1 honours degree or equivalent.

Deadline: 18 December 2026.

Interested candidates should review the project page and submit their application through the University of Southampton postgraduate research admissions process before the closing date.

Funding details

Competition funded.

What's required

Applicants should have a 2:1 honours degree or equivalent. The project is open within the Faculty of Engineering and Physical Sciences and is aimed at candidates interested in biomedical research using imaging, human stem-cell models, and organoid systems.

How to apply

Review the project information, entry requirements, and funding details on the University of Southampton project page, then follow the website application instructions for the PhD project before the closing date.

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