PhD in Molecular Basis of Viral Superinfection Exclusion at University of St Andrews University of St Andrews in United Kingdom

PhD opportunity at The Francis Crick Institute with Dr Peter Rosenthal on cryomicroscopy of lipid-enveloped virus entry and assembly . The project sits at the intersection of structural biology , virology , cell biology , and biophysics , with a strong emphasis on cryo-EM , cryo-ET , and related imaging/computational methods. The research aims to directly image key steps in infection by lipid-enveloped viruses such as influenza and retroviruses . Topics include virus entry, receptor binding, mem...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in structural biology, virology, biochemistry, biophysics, and molecular biology . This funded PhD project, supervised by Dr I Taylor , focuses on the ZAP antiviral response and how the proteins ZAP, KHNYN, and Trim25 assemble into molecular complexes that recognize viral RNA and trigger RNA degradation. The project aims to uncover the structure and mechanism of this antiviral system using protein purification, RNA-binding as...

PhD opportunity at the University of St Andrews in the School of Biology: EastBIO: Understanding human sulfatases involved in heparan sulfate degradation . This project sits at the intersection of biochemistry , molecular biology , structural biology , biophysics , and biomedical engineering . The research focuses on human lysosomal sulfatases that act on heparan sulfate, with the goal of understanding their structure, mechanism, function, and disease relevance . The work connects directly to ly...

PhD opportunity at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom on structural and cellular approaches to understand microtubule motors . This project sits at the intersection of cell biology , molecular biology , and structural biology , with a strong focus on microtubule motors such as dynein and kinesin . The research asks how motors are linked to cargos and coordinated to deliver organelles, RNAs, and proteins to the correct destination, especially...