PhD in Signalling and Cytoskeleton Regulation of Vaccinia Virus Egress The Francis Crick Institute in United Kingdom

PhD opportunity at The Francis Crick Institute with Dr Peter Rosenthal on cryomicroscopy of lipid-enveloped virus entry and assembly . The project sits at the intersection of structural biology , virology , cell biology , and biophysics , with a strong emphasis on cryo-EM , cryo-ET , and related imaging/computational methods. The research aims to directly image key steps in infection by lipid-enveloped viruses such as influenza and retroviruses . Topics include virus entry, receptor binding, mem...

PhD opportunity in viral superinfection exclusion at the University of St Andrews This funded PhD project investigates the molecular basis of viral superinfection exclusion (SIE) in two plant RNA viruses. SIE is a process where an established virus infection prevents subsequent infection by the same or closely related viruses, with implications for viral evolution, recombination, and viral vector biotechnology. The project combines biochemistry , biophysics , structural biology , cell biology , ...

PhD opportunity at The Francis Crick Institute in London, United Kingdom: Enabling antibiotics discovery by targeted protein degradation with Dr Francesca Ester Morreale. This funded PhD project focuses on targeted protein degradation (TPD) in pathogenic bacteria as a new strategy for antibiotic discovery . The project will explore how to design novel antibiotic degraders and study their mechanism of action using biochemistry , biophysics , proteomics , and molecular microbiology . The lab’s bro...

PhD opportunity: In situ structural biology of cellular adaptation at The Francis Crick Institute in collaboration with University College London . This 2027 joint PhD project is supervised by Dr Peter Rosenthal (Crick) and Dr Amandine Maréchal (UCL). The project sits at the interface of structural biology , mitochondrial biology , bioenergetics , cell biology , microbiology , biochemistry , and biophysics . The research asks how cells adapt to environmental and metabolic stress by remodeling th...

PhD opportunity in pathological protein assembly in neurodegenerative diseases at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom . The project is centered on the molecular pathology of neurodegeneration, with a focus on amyloid filament formation by disease-associated proteins such as TDP-43 , annexin A11 , and TAF15 . Two PhD project directions are described. One aims to reproduce pathological protein filament structures in vitro using protein biochemist...