Publisher
source

MRC Laboratory of Molecular Biology

PhD in TRIM21 Degradation of Viruses and Aggregates Laboratory of Molecular Biology in United Kingdom

Degree Level

PhD

Field of study

Immunology

Funding

Competition Funded PhD Project (Students Worldwide). Funding is indicated, but the post does not specify stipend amount, tuition coverage details, or other financial terms.

Deadline

Dec 8, 2026

Country flag

Country

United Kingdom

University

MRC Laboratory of Molecular Biology

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Keywords

Immunology
Molecular Biology
Biophysics
Biology
Structural Biology
Autophagy
Medical Science
Protein Aggregation
Protease
Protein Degradation

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About this position

PhD opportunity at the Laboratory of Molecular Biology in Cambridge, United Kingdom, focused on TRIM21, intracellular antibody immunity, and the degradation of viruses and protein aggregates.

The project explores how TRIM21, a cytosolic E3 ligase and antibody receptor, is activated and regulated, how it recruits different E2 enzymes, and how it can direct substrates to both the proteasome and autophagy. The research is highly relevant to molecular biology, immunology, biophysics, and structural biology, with connections to viral infection and neurodegenerative aggregates such as tau.

This is a competition funded PhD project open to students worldwide. The post does not list a stipend amount or detailed tuition package, but it clearly indicates funded PhD support.

Ideal applicants should be highly motivated and dedicated, with an interest in biology at the molecular and cellular level and a willingness to learn the techniques needed for the project. Training is available across the group and the wider LMB, including structural/biophysical methods and cellular and animal models of infection.

To apply, register your interest via the FindAPhD enquiry page. The university will respond directly after submission.

Deadline: 2026-12-08.

Funding details

Competition Funded PhD Project (Students Worldwide). Funding is indicated, but the post does not specify stipend amount, tuition coverage details, or other financial terms.

What's required

Applicants should be talented, highly motivated, and dedicated researchers with a desire to understand biology at the molecular and cellular level. A willingness to learn whatever techniques are needed is emphasized, and the project welcomes students interested in structural/biophysical approaches as well as cellular and animal models of infection.

How to apply

Register your interest through the FindAPhD enquiry form. The university will respond directly, and you will need a FindAPhD account to view your enquiry and receive updates.

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