Hannes Link
3 months ago
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PhD Position in Genome Engineering and Host-Pathogen Interactions University of Tübingen in Germany
Degree Level
PhD
Field of study
Immunology
Funding
Available
Country
Germany
University
University of Tübingen
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About this position
PhD position at the Cluster of Excellence Controlling Microbes to Fight Infections (CMFI), University of Tübingen, in the Link Lab.
The project focuses on genome engineering, host-pathogen interactions, microbiology, and immunology. The successful candidate will use CRISPR interference (CRISPRi) libraries in E. coli and S. aureus to identify bacterial genes involved in immune evasion, then combine high-throughput immune assays, metabolomic profiling, and LC-MS/MS analysis to discover targets that increase immune visibility of pathogenic bacteria.
This is a collaborative interdisciplinary project with the Mager Lab (immunology), including dendritic cell reporter assays and analysis of bacterial surface structures such as LPS and wall teichoic acids. The position is initially limited to three years and is to be filled as soon as possible.
Eligibility highlights: a Masters degree in biotechnology, microbiology, molecular biology, or a related field; background in microbial genetics, molecular biology, or infection biology; and strong English communication skills. Experience with CRISPR methods, cloning, bacterial genetics, metabolomics, mass spectrometry, Python, or R is advantageous.
How to apply: email one PDF containing a cover letter, CV, and relevant certificates to [email protected]. Applications are reviewed from 2026-04-01 until the position is filled.
Funding details
Available
What's required
Applicants should hold a Masters degree in biotechnology, microbiology, molecular biology, or a related field. A background in microbial genetics, molecular biology, or infection biology is required. Experience with CRISPR-based methods, molecular cloning, or bacterial genetics is a plus, as is experience with metabolomics, mass spectrometry, or data analysis using Python or R. Excellent written and spoken English skills and strong motivation to work at the interface of microbiology and immunology are expected.
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Professors
Professor
Germany
Research Interests
Microbiology
Immunology
Biology
Metabolomic
Metabolic Engineering
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.