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Institute of Chemical Technology

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PhD Position in Glycochemistry and Synthesis of N-Acetyl-Glucosamine Analogues as Therapeutic Agents Institut de Chimie des Substances Naturelles in France

Degree Level

PhD

Field of study

Chemistry

Funding

Temporary full-time PhD contract (35 hours/week). The post is funded through the ANR Gb3Down project, not through an EU research framework programme. No stipend amount or tuition details are stated.

Deadline

Oct 30, 2026

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Country

France

University

Institute of Chemical Technology

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Keywords

Chemistry
Biology
Mass Spectrometry
Medical Science
Hplc
Carbohydrate Chemistry
Nmr Spectroscopy
Pharmaceutical Chemistry
Glycosylation

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About this position

PhD position in glycochemistry at the Institut de Chimie des Substances Naturelles (ICSN), CNRS, part of Université Paris-Saclay, in Gif-sur-Yvette, France.

The project focuses on the synthesis of N-acetyl-glucosamine analogues as therapeutic agents within the ANR Gb3Down project. The successful candidate will join the carbohydrate chemistry team in the Department of Chemical Biology and work under the supervision of the team leader, with joint supervision by two researchers.

Research topics include organic synthesis, carbohydrate chemistry, glycosylation, selective protection/deprotection strategies, and structural modification at the anomeric position, amino group, and hydroxyl groups. Compounds will be characterized using NMR spectroscopy, mass spectrometry, and HPLC, and biological activity will be evaluated with project partners in cellular assays and in vivo studies.

Eligibility highlights: a Master’s degree (M2) in Organic Chemistry, Medicinal Chemistry, or an equivalent qualification; specialization in organic synthesis and/or glycochemistry; experience in multi-step synthesis is strongly valued; basic French is required; and strong autonomy, rigor, teamwork, scientific writing, and oral presentation skills are expected.

Funding information: the position is a temporary full-time PhD contract (35 hours/week). No stipend amount is stated. The post is not funded by an EU programme.

Deadline: 30 October 2026, 23:59 UTC. How to apply: submit your application through the CNRS job portal and consult the additional job details page. A Euraxess link is also provided for viewing or applying.

Funding details

Temporary full-time PhD contract (35 hours/week). The post is funded through the ANR Gb3Down project, not through an EU research framework programme. No stipend amount or tuition details are stated.

What's required

Master's degree (M2) in Organic Chemistry, Medicinal Chemistry, or an equivalent qualification; specialization in organic synthesis and/or glycochemistry; demonstrated experience in multi-step synthesis including protection/deprotection and glycosylation is highly appreciated; strong proficiency in NMR spectroscopy, mass spectrometry, and HPLC; interest in medicinal chemistry and therapeutic applications; autonomy, rigor, teamwork in a multidisciplinary chemist-biologist environment; good scientific writing and oral presentation skills; basic French language level.

How to apply

Apply via the CNRS job portal using the provided application website. Review the additional job details page and submit the application before the deadline. The post also links to the Euraxess application page for viewing or applying.

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