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University of Bern

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PhD Position in Precision Treatment Selection for Major Depressive Disorder Using EEG, ECG and MRI Biomarkers University of Bern in Switzerland

Degree Level

PhD

Field of study

Psychology

Funding

The position is a 100% temporary employment limited to four years. The project is funded by the Swiss National Science Foundation with CHF 1.99 million, providing comprehensive structural support for the interdisciplinary research environment. Individual salary and tuition details are not stated.

Country flag

Country

Switzerland

University

University of Bern

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Keywords

Psychology
Randomized Controlled Trial
Electrophysiology
Health Economics
Neuropsychology
Clinical Psychology
Medical Science
Magnetic Resonance Imaging
Major Depressive Disorder
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About this position

The University of Bern is offering a PhD position in the multicenter project PRECISE-MDD, investigating precision treatment selection in major depressive disorder. The study is a triple-blind randomized controlled trial examining whether EEG- and ECG-based biomarkers can predict the therapeutic effects of antidepressants, repetitive transcranial magnetic stimulation, ketamine and electroconvulsive therapy in patients with unipolar depression.

At the Bern study center, the doctoral researcher will contribute to state-of-the-art magnetic resonance imaging conducted at the Swiss Institute for Translational and Entrepreneurial Medicine in cooperation with the Neuroradiology Department at Inselspital Bern. The project will assess changes in structural and functional brain connectivity that may be associated with treatment response, alongside clinical, mechanistic and health-economic outcomes.

The researcher will coordinate study activities at the Bern site with the interdisciplinary team and collaborate with doctoral researchers in Zurich and Basel. The work includes patient recruitment and screening, randomization, clinical visits and follow-up assessments, as well as clinical interviews, psychometric testing, EEG, ECG and MRI procedures. The doctoral candidate will also contribute to neurophysiological quality assurance, REDCap-based study documentation, clinical trial monitoring, data preparation, statistical analyses and MRI analyses.

The position offers a broad clinical and neurobiological research environment in affective disorders, with opportunities to supervise master’s students and research interns, present findings at national and international conferences, and publish scientific work leading toward a PhD. The research is based at the University Psychiatric Center Bern within the Directorate of Teaching and Research, under the direction of Tobias Bracht, Leila Soravia and Bogdan Draganski, with partner centers at the psychiatric university hospitals in Zurich and Basel.

The interdisciplinary team, research infrastructure and international network support further development in neuropsychiatry, clinical psychiatry and psychology.

Funding details

The position is a 100% temporary employment limited to four years. The project is funded by the Swiss National Science Foundation with CHF 1.99 million, providing comprehensive structural support for the interdisciplinary research environment. Individual salary and tuition details are not stated.

What's required

Applicants must have a master's degree in psychology or neuroscience, or a completed medical degree. Experience in clinical research is required or strongly relevant, with experience conducting or coordinating randomized controlled trials particularly welcome. Candidates should be interested in affective disorders, neurobiology, neurophysiology, MRI imaging and clinical research; be highly motivated to learn new research methods; demonstrate initiative, reliability and careful working habits; enjoy both independent and team-based work; be comfortable communicating with patients; and have very good German and English skills.

How to apply

Submit your application through the “Apply” button on the University of Bern vacancy page. For questions about the position, contact Prof. Dr. med. Tobias Bracht; application questions can be directed to Nicole Portner.

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