Publisher
source

Niall Barron

1 year ago

PhD Position: Tools to Target Epitranscriptomic Modifications on Transgenic mRNA University of Udine in Italy

Degree Level

PhD

Field of study

Cell Biology

Funding

Funded PhD Project (Students Worldwide)

Deadline

Expired

Country flag

Country

Italy

University

University of Udine

Suggested positions

Publisher
source

Icahn School of Medicine at Mount Sinai

Country flag

United States

Postdoctoral Fellow opportunity in Genome Engineering at the Jiang Lab , Icahn School of Medicine at Mount Sinai, New York City, United States. The lab is seeking a highly motivated postdoctoral researcher to work on CRISPR-based genome editing and translational gene therapy approaches aimed at correcting or modeling disease-causing mutations, including applications relevant to human genetic disease such as cystic fibrosis. Research areas include mammalian cell culture, transfection, electropora...

Cell Biology
Molecular Biology
Biomedical Engineering
+6 more

1 week ago

Publisher
source

Onur Hastürk

Sabanci University

Country flag

Turkey

SU SilkLab at Sabanci University is announcing two PhD student openings and one postdoctoral researcher position in a TÜBİTAK 2232-B-funded project. The project focuses on development of transgenic silkworm strains and novel silkworm-derived cell lines for spider silk biosynthesis . Research directions include genetic engineering, transgenic silkworm technology, silkworm cell culture, and recombinant production of spider silk proteins using innovative biosynthetic platforms. This opportunity is ...

Molecular Biology
Biomedical Engineering
Chemical Engineering
+5 more

1 week ago

Publisher
source

University of Oxford

Country flag

United Kingdom

Funded DPhil/PhD opportunities are available in Therapeutic Genomics through the MRC Centre of Research Excellence in Therapeutic Genomics (MRC CoRE-TG), with projects at the University of Oxford and Newcastle University . Projects combine experimental and translational research and may involve molecular and cellular biology , genomic technologies , disease models , CRISPR , antisense oligonucleotides , computational analysis, and therapeutic development aimed at advancing genome-targeted therap...

Cell Biology
Molecular Biology
Biomedical Engineering
+5 more

1 month ago

Publisher
source

Baylor College of Medicine

Country flag

United States

Postdoctoral Associate position in cell and gene therapy at Baylor College of Medicine in Houston, Texas, within the Texas Children's Cancer Center and the Center for Advanced Innate Cell Therapy . The project focuses on cancer immunology and immunotherapy , especially developing and testing novel CAR-redirected immunotherapy for pediatric solid tumors . The research includes gene knockout and knock-in screens to identify and therapeutically target regulators of immune effector cell antitumor ac...

Molecular Biology
Immunotherapy
Biomedical Engineering
+6 more

1 week ago

Publisher
source

Spartan Therapeutics Pty Ltd

Country flag

Australia

Research Associate – Protein Purification at Federated Biologics Pty Ltd in Alexandria, Sydney, Australia. This is a full-time laboratory role focused on protein purification, biologics process development, and day-to-day chromatographic work in a small, fast-moving commercial team. The successful candidate will own routine protein purification activities and help generate dependable data for process development and customer programs. Research focus and responsibilities: protein A capture and po...

Biochemistry
Molecular Biology
Biomedical Engineering
+6 more

1 week ago

Keywords

Cell Biology
Molecular Biology
Biomedical Engineering
Biotechnology
Biology
Health Science
Gene Therapy
Tissue Engineering
Rna Biology
Biopharmaceutics
Transgenic Technology
Dna Methylation
Omics
Genome Engineering
Monoclonal Antibodies
Translation Biology

About this position

This PhD project, hosted at the University of Udine in collaboration with the National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland, focuses on developing innovative tools to target epitranscriptomic modifications on transgenic mRNA. The research is motivated by the growing interest in mRNAs as vaccines and therapeutics, especially following the success of Covid-19 mRNA vaccines. The project aims to engineer biotherapeutic production cell lines by programming host cells to introduce or remove specific mRNA methylation events, thereby improving the yield and stability of biotherapeutics. Key objectives include selectively deleting or overexpressing genes involved in RNA methylation in CHO, HEK293, and other target cells, creating transgenic cell lines that stably express programmable RNA methyltransferases or demethylases, and examining the productivity of recombinant proteins and viral gene therapy vectors from these novel host cell lines.

The host laboratory specializes in understanding and improving cell systems for manufacturing biological medicines, with a focus on cellular molecular mechanisms and advanced omics technologies. The research involves genetic engineering strategies to enhance host cell lines for efficient production of monoclonal antibodies, therapeutic proteins, and viral gene therapy vectors. The project includes secondments to collaborating laboratories at University College Dublin and baseclick GmbH in Germany.

Applicants should have a BSc or Master’s degree in Biology, Biotechnology, or a related field, and must not already possess a doctoral degree. Research experience in cellular and molecular biology is required, with RNA biology experience considered a strong advantage. Proficiency in English and good communication skills are essential. The application process requires a statement of interest, CV, university examination certificate, and a final degree certificate translated into English, all merged into a single PDF.

The deadline for applications is January 31, 2026. For more information, candidates can visit the INT2ACT project website or contact the project coordinator.

Funding details

Funded PhD Project (Students Worldwide)

What's required

Applicants must hold a BSc or Master’s degree in Biology, Biotechnology, or a related field and must not already possess a doctoral degree. Candidates must comply with the mobility rule, meaning they should not have resided or carried out their main activity in Ireland for more than 12 months in the 36 months immediately before recruitment. Research experience in cellular and molecular biology techniques is required, and experience in RNA biology is a strong advantage. Proficiency in English is required, demonstrated by an English test (IELTS, TOEFL, Cambridge English) unless exempted by nationality or previous education. Good oral and written communication skills are necessary.

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts and confirm requirements with the university.

Professors

Professor at INT2ACT

University Name
Country flag

Italy

Research Interests

Tissue Engineering

Cell Biology

Translation Biology

Biology

Biotechnology

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Cell Biology

Tissue Engineering

Monoclonal Antibodies

Molecular Biology

Health Science

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Tissue Engineering

Cell Biology

Biopharmaceutics

Omics

Monoclonal Antibodies

Dr. at INT2ACT

University Name
Country flag

Italy

Research Interests

Tissue Engineering

Biochemistry

Biomedical Engineering

Health Science

Biotechnology