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Ludwig-Maximilians-Universität München
2 days ago
PhD Student in Placental Biology and Chromatin Regulation of Early Development Ludwig-Maximilians-Universität München in Germany
Degree Level
PhD
Field of study
Molecular Biology
Funding
The position is part-time at 65% and remunerated according to TV-L E13. It is limited to three years. The advert also states that employees receive an annual special payment, 30 days of vacation, and an additional pension scheme, together with other LMU employee benefits.
Deadline
Nov 15, 2026
Country
Germany
University
Ludwig-Maximilians-Universität München
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About this position
Ludwig-Maximilians-Universität München is offering a PhD project in Placental Biology at the Biomedical Center Munich (BMC), Institute of Physiological Chemistry, in Planegg, Germany.
The research investigates how a conserved chromatin regulatory network safeguards early development, with particular emphasis on the extra-embryonic lineage and its communication with the developing embryo. The project will examine how disruption of this network in the placenta can influence fetal brain development through non-cell-autonomous mechanisms, and will seek to identify the metabolic and epigenomic signals involved.
The PhD student will establish, expand, and maintain conditional mouse lines; perform timed matings, embryo staging, and coordinated tissue collection; and characterize embryonic and extra-embryonic tissues using molecular, cellular, and histological approaches. Additional work will involve culturing and genetically manipulating murine stem cell lines, including CRISPR/Cas9 editing and clonal validation.
Functional and phenotypic assays will include flow cytometry, imaging, and expression analyses. The student will prepare samples for genomics, epigenomics, and metabolomics pipelines and collaborate with bioinformatics partners to integrate and interpret multi-omics datasets. The role also includes mentoring Bachelor’s and Master’s students, contributing to publications and presentations, and participating in teaching within the Physiological Chemistry Department.
The project is based in the BMC on the Martinsried Campus, a major scientific location with close connections to the LMU University Hospital, chemistry and biology faculties, DZNE-Munich, Helmholtz Center Munich, Max Planck Institutes, and biotechnology organizations. The successful candidate will join a motivated international team in a modern, well-equipped research environment with opportunities for training, career development, conference participation, and international collaboration.
Funding details
The position is part-time at 65% and remunerated according to TV-L E13. It is limited to three years. The advert also states that employees receive an annual special payment, 30 days of vacation, and an additional pension scheme, together with other LMU employee benefits.
What's required
Applicants must have a Master's degree or comparable qualification in biology, biochemistry, pharmacy, medicine, or a related natural science discipline. A keen interest in mouse development and molecular biology is required, as is willingness to work experimentally with laboratory animals in preclinical mouse models. FELASA B certification or equivalent is an asset and can be acquired on site. Practical cell-culture experience is desirable, very good English is required, and applicants should demonstrate strong organizational and teamwork skills, flexibility, curiosity, responsibility, passion for research, and an interest in independent scientific work. Basic bioinformatics skills such as R, Python, or command-line handling of sequencing data are advantageous.
How to apply
Submit the complete application package exclusively through the LMU online application platform by 15 November 2026. Include an English CV of no more than two pages, the requested Master's research and research-interest descriptions, transcripts and degree certificates, provisional transcripts where applicable, and contact details for at least two referees.
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