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Ludwig-Maximilians-Universität München

PhD Student in Placental Biology and Chromatin Regulation of Early Development Ludwig-Maximilians-Universität München in Germany

Degree Level

PhD

Field of study

Molecular Biology

Funding

The position is part-time at 65% and remunerated according to TV-L E13. It is limited to three years. The advert also states that employees receive an annual special payment, 30 days of vacation, and an additional pension scheme, together with other LMU employee benefits.

Deadline

Nov 15, 2026

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Country

Germany

University

Ludwig-Maximilians-Universität München

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Keywords

Molecular Biology
Biology
Developmental Biology
Neuropsychology
Embryology
Medical Science
Omics
Epigenetic
Placental Biology
Metabolomic

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PhD Student in Placental Biology at the Ludwig Maximilian University of Munich’s Biomedical Center (BMC) in Munich. The project explores the earliest stages of post-implantation development, focusing on how the developing embryo and placenta begin exchanging signals. The research examines how chromatin regulation helps establish and maintain communication between embryonic and placental tissues. The doctoral researcher will use mouse genetics, stem-cell-based approaches and multi-omics to invest...

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About this position

Ludwig-Maximilians-Universität München is offering a PhD project in Placental Biology at the Biomedical Center Munich (BMC), Institute of Physiological Chemistry, in Planegg, Germany.

The research investigates how a conserved chromatin regulatory network safeguards early development, with particular emphasis on the extra-embryonic lineage and its communication with the developing embryo. The project will examine how disruption of this network in the placenta can influence fetal brain development through non-cell-autonomous mechanisms, and will seek to identify the metabolic and epigenomic signals involved.

The PhD student will establish, expand, and maintain conditional mouse lines; perform timed matings, embryo staging, and coordinated tissue collection; and characterize embryonic and extra-embryonic tissues using molecular, cellular, and histological approaches. Additional work will involve culturing and genetically manipulating murine stem cell lines, including CRISPR/Cas9 editing and clonal validation.

Functional and phenotypic assays will include flow cytometry, imaging, and expression analyses. The student will prepare samples for genomics, epigenomics, and metabolomics pipelines and collaborate with bioinformatics partners to integrate and interpret multi-omics datasets. The role also includes mentoring Bachelor’s and Master’s students, contributing to publications and presentations, and participating in teaching within the Physiological Chemistry Department.

The project is based in the BMC on the Martinsried Campus, a major scientific location with close connections to the LMU University Hospital, chemistry and biology faculties, DZNE-Munich, Helmholtz Center Munich, Max Planck Institutes, and biotechnology organizations. The successful candidate will join a motivated international team in a modern, well-equipped research environment with opportunities for training, career development, conference participation, and international collaboration.

Funding details

The position is part-time at 65% and remunerated according to TV-L E13. It is limited to three years. The advert also states that employees receive an annual special payment, 30 days of vacation, and an additional pension scheme, together with other LMU employee benefits.

What's required

Applicants must have a Master's degree or comparable qualification in biology, biochemistry, pharmacy, medicine, or a related natural science discipline. A keen interest in mouse development and molecular biology is required, as is willingness to work experimentally with laboratory animals in preclinical mouse models. FELASA B certification or equivalent is an asset and can be acquired on site. Practical cell-culture experience is desirable, very good English is required, and applicants should demonstrate strong organizational and teamwork skills, flexibility, curiosity, responsibility, passion for research, and an interest in independent scientific work. Basic bioinformatics skills such as R, Python, or command-line handling of sequencing data are advantageous.

How to apply

Submit the complete application package exclusively through the LMU online application platform by 15 November 2026. Include an English CV of no more than two pages, the requested Master's research and research-interest descriptions, transcripts and degree certificates, provisional transcripts where applicable, and contact details for at least two referees.

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