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Mathias Munschauer
3 days ago
PhD Student Position in RNA Biology and Therapeutic mRNA Development Heidelberg University in Germany
Degree Level
PhD
Field of study
Cell Biology
Funding
Part-time employment at 65% under the TV-L E 13 remuneration scale, with an attractive employer-funded pension scheme through VBL. The position includes 30 days of annual leave and additional benefits including a Deutschlandticket, family-support services, health and sports programmes.
Country
Germany
University
Heidelberg University
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Keywords
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About this position
Heidelberg University’s Munschauer Lab at the Centre for Integrative Infectious Disease Research is seeking a doctoral researcher in RNA biology. The project forms part of the DFG Collaborative Research Centre CRC/TRR 440 smART and explores how RNA interactions can be harnessed to improve therapeutic messenger RNA.
The PhD researcher will dissect and characterize cellular RNA-protein interactions with high spatial and temporal resolution. The work includes recombinant production and purification of RNA-binding proteins, analysis of their binding preferences using biochemical and biophysical methods, and in-vitro synthesis of mRNA for formulation into lipid nanoparticle delivery systems.
The project will also investigate lipid nanoparticle quality and use cell-based assays to study RNA delivery, intracellular transport, stability, translation, decay and payload expression. The researcher will work at the interface of experimental RNA biology, RNA biochemistry and bioinformatics, collaborating closely with wet-lab scientists and bioinformaticians across the interdisciplinary CRC/TRR 440 smART network.
The international research environment provides access to RNA biochemistry, cell biology, mass spectrometry, genomics, single-cell transcriptomics and bioinformatics approaches. Doctoral training is supported through the Department of Infectious Diseases and the integrated CRC/TRR 440 smART graduate school, with opportunities for scientific networking, collaborative activities, retreats and a summer school.
Funding details
Part-time employment at 65% under the TV-L E 13 remuneration scale, with an attractive employer-funded pension scheme through VBL. The position includes 30 days of annual leave and additional benefits including a Deutschlandticket, family-support services, health and sports programmes.
What's required
Applicants must hold a Master's degree or equivalent qualification in cell biology, biochemistry, or a related natural or life sciences field. Practical experience in RNA biochemistry, cell biology, and biophysical methods is advantageous; prior lipid nanoparticle formulation experience is beneficial but not required. Professional proficiency in written and spoken English, scientific curiosity, accuracy, independent research ability, and enthusiasm for interdisciplinary teamwork are expected. A valid measles immunity certificate is required for employment at the UKHD.
How to apply
Submit your application directly online through the Heidelberg University Hospital application portal. For further information, contact Prof. Dr. Mathias Munschauer by email at [email protected].
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Professors
Professor, Head of Molecular Virology
Germany
Research Interests
Virology
Biochemistry
Biomedical Engineering
Genomic
Bioinformatic
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