PhD Studentship - Running on Empty: Metabolic Ageing in Blood Stem Cells University of East Anglia in United Kingdom

PhD opportunity at the University of Edinburgh in pancreatic β-cell RNA biology, insulin biosynthesis, and post-transcriptional regulation. This EASTBIO BBSRC Doctoral Training Partnership project investigates how pancreatic β-cell RNA binding proteins (RBPs) regulate insulin mRNA localisation, translation, stability, and decay under euglycaemic and hyperglycaemic conditions. The work aims to uncover the molecular links between glucose metabolism, RBP regulation, and β-cell dysfunction in type 2...

PhD opportunity at the University of East Anglia (Norwich Medical School) in blood stem cell biology , clonal haematopoiesis , ageing , immunology , genetics , cell biology , bioinformatics , and metabolism . This project, A Hostile Niche: How Mutant Blood Stem Cells Damage Their Healthy Neighbours , is supervised by Dr Jayna Mistry and based in the Mistry and Rushworth Lab at Norwich Medical School, UEA , with collaborators across the Norwich Research Park and the Earlham Institute . The resear...

PhD opportunity in human haematopoietic stem cell biology at the University of Cambridge , hosted by the Cambridge Stem Cell Institute and the Laurenti Group . The project focuses on how human blood stem cells function in health and disease , including their unique biology compared with other blood cell types, the effects of ageing and inflammation , and what happens during the early stages of cancer development . The lab uses single-cell biology , including functional single-cell assays and sin...

PhD opportunity at the John Innes Centre in Norwich, United Kingdom, within the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP). The project asks how connections between plant cells and their neighbours control how a cell responds, focusing on plasmodesmata, cell-to-cell connectivity, and immune-associated gene expression. The research explores how plasmodesmal opening/closure affects the movement of molecules between cells and how this relates to plant responses to pathog...

The dark side of DNA is a fully funded PhD project at the Babraham Institute in Cambridge, United Kingdom, within the Epigenetics Programme and the BioSCaPe doctoral training partnership. The project explores how cytosolic DNA arises from the nucleus, how it is processed, and how it may contribute to ageing , DNA repair -related disease, and immune activation. The research combines genomics , molecular genetics , immunology , developmental biology , and bioinformatics . Research aims include pro...