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Sanquin
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Post-doc position on Multi-omics Sanquin Blood Supply Foundation in Netherlands
Degree Level
Postdoc
Field of study
Computer Science
Funding
Available
Deadline
Nov 12, 2026
Country
Netherlands
University
Sanquin
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About this position
Post-doc position on Multi-omics in Hereditary Fibrinogen Disorders: Bridging the Genotype-Phenotype Gap
This postdoctoral project sits within the Fibromics consortium at Sanquin Research in Amsterdam and focuses on hereditary fibrinogen disorders, which are clinically challenging because bleeding and thrombosis risk can be unpredictable. The aim is to bridge the genotype-phenotype gap by identifying phenotype-specific molecular signatures linked to congenital fibrinogen disorders.
The project combines plasma, fibrin clot, and platelet proteomics with protein variant mapping, fibrinogen proteolysis assays, fibrin network structure analysis, genetic data, and clinical characteristics from an established cohort of individuals with congenital fibrinogen disorders. The work brings together mass spectrometry-based proteomics, multi-omics data integration, and clinical phenotyping to better understand the molecular mechanisms underlying these disorders.
You will join the proteomics laboratory at Sanquin Research and work in a multidisciplinary environment that connects fundamental researchers, clinicians, data scientists, and specialized laboratory staff. The international Fibromics consortium links large patient cohorts and leading researchers in hemostasis, proteomics, bioinformatics, and clinical hematology across several European centres, creating a collaborative setting with access to advanced analytical technologies and computational platforms.
The role is embedded in a research program with strong clinical relevance and international visibility, offering opportunities to contribute to cutting-edge cohort studies and to work closely with experts in hemostasis, proteomics, and data science.
Funding details
Available
What's required
Applicants must hold a recent PhD degree in a related field. The advert asks for advanced expertise in mass spectrometry-based proteomics, programming skills such as R or Python, and statistical analysis. Analytical thinking, a strong interest in protein biology, and enthusiasm for integrating biomedical, clinical, and laboratory data using machine learning and AI are expected. Expertise in genomics and molecular biology is an advantage. Excellent communication and writing skills in English and motivation to work collaboratively in an interdisciplinary research environment are required.
How to apply
Submit your CV, academic transcripts, a motivation letter, and contact details for at least two references through the application link. For questions, contact Dr. Maartje van den Biggelaar by email.
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Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.