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Worcester Polytechnic Institute

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Post-Doctoral Fellow: RNA metabolism and mutation tolerance in Mycobacterium tuberculosis Worcester Polytechnic Institute in United States

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Funded by the US National Institutes of Health and the US-Israel Binational Science Foundation; salary $60,000-$63,480 per year.

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Country

United States

University

Worcester Polytechnic Institute

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Keywords

Biochemistry
Molecular Biology
Microbiology
Biology
Medical Science
Genetic
Genomic
Transcriptomic

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About this position

This postdoctoral position is based in Scarlet Shell’s lab in the Department of Biology & Biotechnology at Worcester Polytechnic Institute (WPI). The project centers on how Mycobacterium tuberculosis manages the relationship between RNA metabolism and mutation tolerance, with a particular focus on the ways this pathogen mitigates fitness costs caused by mutations selected during antibiotic exposure and other infection-related stressors.

The successful fellow will contribute to a research program aimed at understanding the regulatory mechanisms that help mycobacterial pathogens tolerate stress and preserve fitness under disease-relevant conditions. The work combines complementary approaches in biochemistry, genetics, genomics, transcriptomics, and phenotypic profiling, offering a broad and interdisciplinary research experience in bacterial pathogenesis and molecular mechanisms of stress adaptation.

The position is housed in WPI’s Life Sciences and Bioengineering Center, a modern research facility designed for collaborative and interdisciplinary science. The broader environment at WPI emphasizes science and engineering research, and the lab’s location in Worcester provides connections to the greater Boston research ecosystem.

Funding details

Funded by the US National Institutes of Health and the US-Israel Binational Science Foundation; salary $60,000-$63,480 per year.

What's required

The successful candidate must have a Ph.D. in a relevant discipline, an excellent work ethic, and a strong background in molecular biology. A solid publication record and experience in biochemistry and microbiology are also desirable.

How to apply

Submit a CV, a cover letter describing your research experience and professional goals, and contact information for at least three professional references. Direct questions to Dr. Shell by email.

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