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CNRS
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6 days ago
Postdoc en biologie moléculaire et biochimie CNRS in France
Degree Level
Postdoc
Field of study
Biochemistry
Funding
Available
Deadline
Nov 13, 2026
Country
France
University
CNRS
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About this position
The EVOGEN team at the Institut de Biologie Intégrative de la Cellule (I2BC) is recruiting a postdoctoral researcher to study how an heterochromatin protein functions during Drosophila spermatogenesis. The project focuses on the Paris sex-ratio (SR) system in Drosophila simulans, a natural meiotic drive context that biases offspring sex ratio through abnormal segregation of sex chromosomes.
The successful candidate will investigate HP1D2, a heterochromatin protein linked to the Y chromosome and associated with the SR phenotype. The work is designed to clarify how HP1D2 contributes to meiotic perturbation and sperm development, combining chromatin biology, genetics, and functional analysis in testes.
- mapping HP1D2-bound sequences on the Y chromosome using CUT&Tag in Drosophila testes,
- identifying HP1D2-associated protein partners using TurboID proximity labelling,
- generating and phenotyping an HP1D2 knockout line to assess its impact on spermatogenesis.
The position is embedded in the EVOGEN research environment at I2BC, which works on intragenomic conflict and evolution. The project offers a strong molecular biology and biochemical framework for studying chromatin regulation in a genetically tractable model organism.
Funding details
Available
How to apply
Apply through the listed public service job portal using the provided application link. Follow the portal instructions and submit the requested application materials before the deadline.
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