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CNRS

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Postdoc en biologie moléculaire et biochimie CNRS in France

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Available

Deadline

Nov 13, 2026

Country flag

Country

France

University

CNRS

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Keywords

Biochemistry
Molecular Biology
Biology
Drosophila Research
Meiosis
Genetic
Transgenesis
Spermatogenesis

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About this position

The EVOGEN team at the Institut de Biologie Intégrative de la Cellule (I2BC) is recruiting a postdoctoral researcher to study how an heterochromatin protein functions during Drosophila spermatogenesis. The project focuses on the Paris sex-ratio (SR) system in Drosophila simulans, a natural meiotic drive context that biases offspring sex ratio through abnormal segregation of sex chromosomes.

The successful candidate will investigate HP1D2, a heterochromatin protein linked to the Y chromosome and associated with the SR phenotype. The work is designed to clarify how HP1D2 contributes to meiotic perturbation and sperm development, combining chromatin biology, genetics, and functional analysis in testes.

  • mapping HP1D2-bound sequences on the Y chromosome using CUT&Tag in Drosophila testes,
  • identifying HP1D2-associated protein partners using TurboID proximity labelling,
  • generating and phenotyping an HP1D2 knockout line to assess its impact on spermatogenesis.

The position is embedded in the EVOGEN research environment at I2BC, which works on intragenomic conflict and evolution. The project offers a strong molecular biology and biochemical framework for studying chromatin regulation in a genetically tractable model organism.

Funding details

Available

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