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Roland Brock

2 months ago

Postdoc in Targeted Oligonucleotide Delivery for Inflammatory Kidney Diseases Radboud University Medical Center in Netherlands

Degree Level

Postdoc

Field of study

Chemistry

Funding

Fixed-term postdoctoral employment for 1.5 years (18 months), starting 1 October 2026 with a later start date possible. Salary is listed as €3,724 - €5,867 on scale 10, with standard employment benefits.

Deadline

Sep 15, 2026

Country flag

Country

Netherlands

University

Radboud University Medical Center

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Keywords

Chemistry
Biomedical Engineering
Materials Science
Biology
Microscopy
Mass Spectrometry
Medical Science
Nanomedicine
Light Scattering

About this position

Radboud University Medical Center is recruiting a Postdoc for a project on targeted oligonucleotide delivery in inflammatory kidney diseases in Nijmegen, Netherlands.

The project focuses on application-oriented development of cellular targeting strategies for antisense oligonucleotides, siRNA, and mRNA, with an emphasis on coupling oligonucleotides to targeting ligands, optimizing analytical and coupling protocols, and evaluating activity and toxicity in preclinical models. The successful candidate will independently design, perform, and analyze experiments aimed at improving cellular targeting and advancing formulations toward late-stage preclinical development.

The position is based in the Targeted Nanomedicines group of Prof. Dr. Roland Brock at Radboudumc, in close collaboration with Mercurna B.V., a biotech company developing targeted therapies for chronic inflammatory kidney disease. The collaboration is local and coordinated closely in Nijmegen.

Research keywords: oligonucleotide delivery, targeted nanomedicines, inflammatory kidney disease, biomolecular conjugation, mass spectrometry, dynamic light scattering, confocal microscopy, preclinical development.

Eligibility highlights: experience with biomolecular conjugation strategies and analytical techniques such as mass spectrometry and dynamic light scattering is expected; standard biochemical and cell biological skills are also required. Confocal microscopy experience is desirable. Applicants should be able to work independently, understand process optimization and standardization, and document protocols carefully. A Certificate of Conduct (VOG) is required.

Funding and contract: fixed-term employment for 18 months (1.5 years), starting 1 October 2026, with a later start date possible. Salary is listed at €3,724–€5,867 (scale 10), plus standard employment benefits.

Application deadline: 15 September 2026.

How to apply: submit the application form on the vacancy page and upload your CV and cover letter. Optional supporting documents can also be added.

Funding details

Fixed-term postdoctoral employment for 1.5 years (18 months), starting 1 October 2026 with a later start date possible. Salary is listed as €3,724 - €5,867 on scale 10, with standard employment benefits.

What's required

Applicants should have experience in biomolecular conjugation strategies and analytical techniques such as mass spectrometry and dynamic light scattering, in addition to standard biochemical and cell biological techniques. Confocal microscopy experience is desirable. The role requires the ability to understand process optimization and standardization, plan and execute experiments independently, analyze results carefully, and document protocols and outcomes thoroughly. A Certificate of Conduct (VOG) is required.

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Professors

Professor

University Name
Country flag

Netherlands

Research Interests

Cell Biology

Biochemistry

Rna Biology

Peptide Chemistry

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