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Singapore-MIT Alliance for Research and Technology

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Postdoctoral Associate in Advanced Microbial Detection for Biopharmaceutical Manufacturing Singapore-MIT Alliance for Research and Technology in Singapore

Degree Level

Postdoc

Field of study

Computer Science

Funding

Available

Country flag

Country

Singapore

University

Singapore-MIT Alliance for Research and Technology

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Keywords

Computer Science
Chemistry
Microbiology
Biomedical Engineering
Biotechnology
Biology
Mass Spectrometry
Medical Science
Ultraviolet Spectroscopy
Biomanufacturing
ML

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About this position

The Singapore-MIT Alliance for Research and Technology (SMART) invites applications for a Postdoctoral Associate working on advanced microbial detection for biopharmaceutical manufacturing. The project is hosted within SMART-CAMP (Critical Analytics for Manufacturing Personalized-Medicine), an interdisciplinary programme spanning Singapore’s CREATE research campus and innovation hub and the Massachusetts Institute of Technology.

The research will develop a novel, label-free and rapid method for detecting microbial contamination in cleaning-validation workflows. The postdoctoral researcher will investigate ultraviolet spectroscopy and machine-learning-assisted approaches for sensitive microorganism detection, combining microbiology, mass spectrometry and spectroscopic methods.

The work will include identifying, verifying and designing analytical methods based on microorganism metabolites, followed by feasibility studies to create a rapid diagnostic tool for safety screening. The researcher will also test and translate rapid detection methods and conduct comparability and benchmarking experiments against compendial microbiology and molecular tests.

The project sits within SMART-CAMP’s broader focus on critical quality attributes and integrated process analytics for cell-therapy manufacturing. The research environment is highly interdisciplinary, bringing together engineers, biologists, clinicians, manufacturing specialists and data-analytics experts from MIT, Singapore-based universities, research centres and hospitals. The postdoctoral researcher will collaborate closely with technical staff from biopharmaceutical companies including GSK, Sanofi and BioNTech, as well as with a research engineer.

Funding details

Available

What's required

A Ph.D. degree in microbiology, biotechnology, or a relevant discipline is essential. Desirable qualifications include demonstrable experience working with bacteria and/or fungi; understanding of metabolite identification and quantification using LC-MS/MS and spectroscopic techniques; and experience or collaborative engagement involving machine learning or modelling. Excellent spoken and written English, strong interpersonal and relationship-building skills, self-motivation, independence, collaboration, organization, analytical ability, and a strong publication, intellectual property, and scientific output record are required or valued. Supervisory experience with junior researchers is expected.

How to apply

Review the official SMART-CAMP job posting and submit an application through the listed application process for the Postdoctoral Associate position.

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