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Astronomical Institute of the Czech Academy of Sciences
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Postdoctoral Fellow / Associate Scientist in Computational Biophysics Heyrovský Institute of the Czech Academy of Sciences in Czech Republic
Degree Level
Postdoc
Field of study
Computer Science
Funding
Available
Deadline
Dec 8, 2026
Country
Czech Republic
University
Astronomical Institute of the Czech Academy of Sciences
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About this position
The Heyrovský Institute of the Czech Academy of Sciences in Prague is recruiting a postdoctoral fellow or associate scientist to join its Computational Biophysics group led by Dr. Štěpán Timr.
The position centers on computational and theoretical research into how molecular environments and spatial organization shape the dynamics, interactions, and biological function of enzymes and proteins. The group combines molecular simulations, coarse-grained modeling, statistical mechanics, and reaction-diffusion approaches to study biological systems across multiple spatial and temporal scales.
The successful researcher will contribute to one of two active directions, depending on expertise and interests:
- protein conformational ensembles, allostery, and molecular crowding;
- spatial organization of enzymes and biochemical reaction pathways, including enzyme localization, molecular diffusion, stochastic reaction kinetics, and extensions of the Spatialzyme framework.
The role is designed for an independent computational scientist who can tackle methodological challenges, critically interpret results, and contribute to ongoing projects and scientific publications. The position offers access to computational resources within a supportive research environment at a leading Czech research institute.
Funding details
Available
What's required
A Ph.D. in biophysics, physics, computational chemistry, applied mathematics, computational biology, or a related field is required. Applicants should have solid practical experience with at least one theoretical or computational approach relevant to the research directions, good programming and quantitative data analysis skills, and experience in independently conducting computational research. Candidates must be able to troubleshoot computational problems, critically evaluate scientific results, recognize model limitations, and propose meaningful next steps. Good communication skills in English and the ability to work both independently and collaboratively are required. Experience with molecular dynamics, protein conformational dynamics, coarse-grained or multiscale modeling, stochastic processes, chemical kinetics, reaction-diffusion modeling, or computational model development is preferred.
How to apply
Prepare a CV including publications, a brief one-page motivation letter, and contact details for two referees. Submit the application through the Teamio application link provided in the advert. Informal enquiries can be sent to [email protected].
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Prepare your application
Review drafts and confirm requirements with the university.