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Statens Serum Institut
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Postdoctoral Fellow in Translational TB Vaccine Development Statens Serum Institut in Denmark
Degree Level
Postdoc
Field of study
Vaccinology
Funding
Available
Deadline
Nov 20, 2026
Country
Denmark
University
Statens Serum Institut
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About this position
This postdoctoral project is based in the TB Vaccine Research Group within the Novo Nordisk Foundation Initiative for Vaccines and Immunity at Statens Serum Institut. The work sits in the Department of Infectious Disease Immunology and the SSI Center for Vaccine Research, in an environment that links basic immunology with translational development and clinical progression.
The project focuses on translational tuberculosis vaccine development, with particular attention to protective immunity in the airways. The successful candidate will help move vaccine concepts from scientific idea towards clinical evaluation by combining mechanistic immunology, preclinical vaccine testing, and biomarker-driven candidate prioritization.
Scientifically, the role centers on understanding why vaccine approaches succeed or fail and using those insights to guide next experiments and strategic decisions. The workstream will compare mucosal and systemic vaccine delivery strategies, platforms, and immunization regimens, starting with an established TB vaccine antigen and later integrating novel antigen constructs from a closely interacting companion project.
The position is embedded in a larger coordinated TB vaccine effort within NIVI, where one project focuses on antibody-mediated immunity and functional B-cell epitopes at the University of Copenhagen, while this postdoctoral fellow leads the in vivo and translational vaccine-evaluation component. Together, the projects aim to develop next-generation TB vaccine strategies that integrate antibody, CD4 T-cell, and CD8 T-cell immunity.
The research group is described as a dynamic international team of scientists, postdoctoral fellows, technicians, PhD students, and translational collaborators. The broader network provides access to complementary expertise, technologies, and research capabilities across SSI and the University of Copenhagen, with opportunities to collaborate across vaccine platforms and disease areas.
The long-term goal is to down-select a promising TB vaccine strategy for validation in advanced animal models and potential prevention-of-infection and prevention-of-disease studies. The role is therefore suited to a researcher who wants to combine detailed experimental work with translational decision-making in a vaccine-development setting.
Funding details
Available
What's required
Applicants should have a PhD in immunology, vaccinology, infectious disease biology, or a related discipline, with a strong scientific foundation in experimental immunology or vaccine research. Hands-on research experience and the ability to design experiments, interpret complex data, and think critically about biological mechanisms are expected. Relevant experience may include cellular immunology, immune phenotyping or advanced flow cytometry, vaccine or infection models, pulmonary, mucosal or tissue-based immunology, T-cell or antibody functional assays, and analysis and communication of complex experimental datasets. Experience with M. tuberculosis, BSL-3 work, animal experimentation, or lung and bronchoalveolar-lavage samples is advantageous but not required. Strong written and spoken English, scientific judgement, curiosity, initiative, and motivation to take ownership are important.
How to apply
Apply electronically via the application link. Include a motivation letter, CV, copies of relevant academic diplomas, a publication list with 2–3 selected scientific works, and contact information for references.
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