Postdoctoral position: Small Molecules that Repartition RNA Conformational Ensembles University of Groningen in Netherlands

Leiden University / Leiden University Medical Center / Leiden Early Drug Discovery and Development (LED3) are advertising a postdoctoral position in medicinal chemistry and chemical biology focused on a synthetic lethality target . The project is described as an exciting collaboration with Sylvie Noordermeer at Leiden University Medical Center, who pioneered the discovery of the synthetic lethal nature of the target. The lab environment is presented as highly collaborative and discovery-oriented...

Two positions are open in the Maglia Lab in Groningen: a PhD student and a postdoc. The research focus is single-molecule nanopore science , a highly interdisciplinary area spanning biology , chemistry , physics , and biomedical engineering . The post invites applicants who want to help push the frontier of nanopore-based single-molecule research. The opportunity is associated with Giovanni Maglia and the Maglia Lab at the University of Groningen in the Netherlands . The post does not provide de...

Leiden University is seeking a postdoctoral researcher to join the Faculty of Science and the Leiden Academic Centre for Drug Research (LACDR) on an interdisciplinary drug discovery project targeting the synthetic lethality target EXO1. The successful candidate will work on an innovative medicinal chemistry and chemical biology campaign aimed at developing new drug modalities. The project includes designing scaffold ideas for covalent and non-covalent inhibitors, optimising new and existing comp...

Leiden University is recruiting a full-time postdoctoral candidate in medicinal chemistry and chemical biology to advance a drug discovery campaign against the synthetic lethality target EXO1. The project is a collaboration between the Pomplun Lab and Sylvie Noordermeer’s group at Leiden University Medical Center (LUMC), based in Leiden, Netherlands. The successful researcher will develop scaffold proposals for covalent and non-covalent inhibitors, optimize novel and existing compound series for...

This postdoctoral project at Leiden University focuses on covalent small-molecule inhibitor discovery for emerging cancer targets. The work is rooted in chemical proteomics and drug discovery for proteins involved in immune-oncology that are considered challenging to address with conventional small molecules. The successful researcher will develop and optimize electrophilic lead compounds, then design bifunctional analogues intended to induce protein degradation. The role combines synthetic and ...