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St. Jude Children's Research Hospital

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Postdoctoral Research Associate in Chemical Biology and Therapeutics St. Jude Children's Research Hospital in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Postdoctoral research associate position; salary is commensurate with experience. No additional funding details, stipend amount, or tuition coverage are stated.

Deadline

Dec 21, 2026

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Country

United States

University

St. Jude Children's Research Hospital

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Keywords

Cell Biology
Molecular Biology
Chemistry
Biomedical Engineering
Biology
Structural Biology
Drug Metabolism
Chemical Biology
Medical Science
Pharmacy
Pharmaceutical Chemistry
Protein Degradation
Nuclear Receptor

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About this position

St. Jude Children's Research Hospital is advertising a Postdoctoral Research Associate position in the laboratory of Taosheng Chen in Memphis, Tennessee, United States.

The project sits at the interface of chemical biology, structural biology, medicinal chemistry, molecular biology, and drug metabolism. The Chen Lab studies xenobiotic sensing, therapeutic response, and the molecular regulation of PXR, CAR, and the drug-metabolizing enzymes CYP3A4 and CYP3A5.

The successful candidate will lead biological characterization of novel ligands, inhibitors, and targeted protein degraders; develop cellular and molecular approaches to study transcriptional networks and selective enzyme modulation; collaborate with structural biologists and chemists; and evaluate chemical probes in cellular and in vivo models.

Applicants should have proven expertise in cell and molecular biology. A working understanding of structural biology, medicinal chemistry, and chemical biology is preferred, and experience or strong interest in nuclear receptor biology, protein degradation, or drug metabolism is valuable.

This is a postdoctoral opening, not a scholarship. Salary is commensurate with experience. The closing date listed is 21 Dec 2026.

Apply through the employer website using the Nature Careers application link.

Funding details

Postdoctoral research associate position; salary is commensurate with experience. No additional funding details, stipend amount, or tuition coverage are stated.

What's required

Applicants should have proven expertise in cell and molecular biology. A working understanding of structural biology, medicinal chemistry, and chemical biology is preferred. Experience or strong interest in chemical biology, nuclear receptor biology, drug metabolism, or protein degradation is valuable. The role suits a scientist able to work independently and lead multidisciplinary biological studies.

How to apply

Apply on the employer website via the Nature Careers application link. Review the job details and submit your application through the external portal before the closing date.

More information can be found here

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