University of North Carolina at Chapel Hill
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Postdoctoral Research Associate in Pulmonary Ozone Response, Epigenomics, and Transcriptomics University of North Carolina at Chapel Hill in United States
Degree Level
Postdoc
Field of study
Environmental Science
Funding
Full-time temporary postdoctoral scholar appointment with a hiring range of $64,000–$74,000, an estimated 12-month duration, and 40 hours per week. UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and additional benefits and services.
Country
United States
University
University of North Carolina at Chapel Hill
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About this position
The Kelada Lab at the University of North Carolina at Chapel Hill is recruiting a postdoctoral research associate for a project on how the air pollutant ozone affects the lungs. The research will investigate why genetically different mice show different pulmonary responses to ozone exposure.
The project will connect DNA sequence variation, chromatin and other epigenomic states, and gene expression changes elicited by ozone in vivo. The team will examine how these molecular features relate to hallmark outcomes including airway inflammation and pulmonary injury.
Using the genetically diverse Collaborative Cross mouse genetics reference population, the postdoctoral researcher will help generate and analyze datasets focused on ozone-induced epigenomic and transcriptomic changes in alveolar macrophages. The work is designed to identify new biological pathways through which ozone exposure produces adverse pulmonary responses.
The researcher will gain experience with genomic analysis techniques, the Collaborative Cross mouse resource, and the molecular effects of ozone on the airway. The UNC pulmonary and toxicology research communities, together with a strong bioinformatics team, will provide opportunities for collaboration and training in transcriptomic analysis and related approaches. The role also includes contributing to scientific papers and presenting research at scientific meetings, supporting preparation for an independent research career in academia or industry.
Funding details
Full-time temporary postdoctoral scholar appointment with a hiring range of $64,000–$74,000, an estimated 12-month duration, and 40 hours per week. UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and additional benefits and services.
What's required
Applicants must hold a PhD in Toxicology, Pharmacology, Immunology, or a related field. Required experience includes in vitro and/or in vivo respiratory or inhalation exposure models, including cellular readouts of exposure-induced pro-inflammatory signaling and/or gene expression. Preferred qualifications include experience analyzing high-throughput sequencing data such as RNA-seq. Candidates should be self-motivated, enthusiastic, and possess strong communication skills. Required application materials are a curriculum vitae or resume, cover letter, list of references, and writing or research sample.
How to apply
Apply through the UNC-Chapel Hill PeopleAdmin posting. Submit a CV or resume, cover letter, list of references, and writing or research sample. The position is open until filled.
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Prepare your application
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ApplyKite TwinLearns as you applyMake your next move.
Prepare your application
Review drafts and confirm requirements with the university.