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University of Oxford

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Postdoctoral Research Associate in Structural Mass Spectrometry (SLC Transporters) University of Oxford in United Kingdom

Degree Level

Postdoc

Field of study

Chemistry

Funding

Fixed-term post funded by the Wellcome Trust for up to 12 months in the first instance. Salary £42,794 to £47,779 per annum, with starting salary dependent on qualifications, relevant skills, and available funding.

Deadline

Nov 9, 2026

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Country

United Kingdom

University

University of Oxford

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Keywords

Chemistry
Biophysics
Biology
Analytical Chemistry
Structural Biology
Mass Spectrometry
Clinical Proteomics
Membrane Protein
Lipidomic

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About this position

University of Oxford is advertising a Postdoctoral Research Associate in Structural Mass Spectrometry within the Department of Biochemistry in Oxford, United Kingdom. The post sits in the Newstead group and the Kavli Institute for Nanoscience, working with Professor Simon Newstead and Dr Jo Parker.

The research focuses on the native mass spectrometry study of solute carrier (SLC) transporters, with broader links to structural biology, biophysical chemistry, analytical chemistry, proteomics, and lipidomics. The role involves leading a discrete MS programme within a larger effort to understand how SLC transporters are folded, modified, trafficked, and regulated in mammalian cells.

This is a fixed-term, full-time position funded by the Wellcome Trust for up to 12 months in the first instance. Salary is listed at £42,794 to £47,779 per annum.

Applicants should hold, or be near completion of, a PhD/DPhil in a relevant discipline and have substantial experience with native top-down mass spectrometry on high-resolution hybrid Orbitrap systems, including Thermo Fisher Orbitrap UHMR and Ascend platforms. Strong practical skills in sample preparation, advanced fragmentation, quantitative analysis of protein modifications and lipid interactions, and computational/data-analysis work are required, ideally with Python. Experience with SLC transporter research, glycoproteomics, open-source software development, and publication strength would be advantageous.

Applications must be submitted online using Vacancy ID 189364. Candidates should upload a CV and supporting statement, and provide details of two referees. The closing date is 9 November 2026 at 12.00 noon.

Funding details

Fixed-term post funded by the Wellcome Trust for up to 12 months in the first instance. Salary £42,794 to £47,779 per annum, with starting salary dependent on qualifications, relevant skills, and available funding.

What's required

Applicants should hold, or be near completion of, a PhD/DPhil in biophysical chemistry, analytical chemistry, structural biology or a related discipline. Required experience includes native top-down mass spectrometry on high-resolution hybrid Orbitrap instrumentation, specifically Thermo Fisher Orbitrap UHMR and Ascend platforms, native MS sample preparation, advanced fragmentation techniques, quantitative analysis of protein modifications and lipid interactions, proteomics, lipidomics, membrane protein expression and purification, and strong computational/data-analysis skills, ideally including Python scientific software development. Experience in SLC transporter research, glycoproteomics, open-source software development, and a strong publication record would be advantageous.

How to apply

Apply online via the 'Apply' button using Vacancy ID 189364. Upload a CV and supporting statement addressing the selection criteria, and provide details of two referees. Direct queries to [email protected].

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