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Dana-Farber Cancer Institute

Postdoctoral Research Fellow in DNA Repair, Genomic Stability and Cancer Biology Dana-Farber Cancer Institute in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Full-time permanent postdoctoral position with a listed salary of $72,000–$76,385.

Deadline

Jan 5, 2027

Country flag

Country

United States

University

Dana-Farber Cancer Institute

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Keywords

Cell Biology
Molecular Biology
Cancer Biology
Biology
Medical Science
Dna Repair
Dna Damage
Chromatin Biology
Genome Stability

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About this position

The D’Andrea Lab at Dana-Farber Cancer Institute in Boston investigates chromosome instability and susceptibility to cancer, with a focus on the molecular signaling pathways that regulate the DNA damage response in mammalian cells.

The postdoctoral researcher will study how disruption of DNA damage-response pathways through germline or somatic mutation contributes to genomic instability, sensitivity to ionizing radiation, defective cell-cycle checkpoints, and impaired DNA repair in human cancers. The work will address DNA repair pathways, replication fork stability, and ubiquitin signaling.

The role offers an opportunity to work in a dynamic, multidisciplinary cancer-research environment using advanced molecular and cellular approaches, including CRISPR/Cas9 gene editing, protein biochemistry, mass spectrometry, and live-cell imaging. The researcher will design and conduct experiments, analyze and interpret data, and present findings at scientific meetings.

The fellow will collaborate with medicinal chemists and clinical researchers, contribute to manuscripts and grant applications, mentor junior team members, and support the broader research environment. Dana-Farber Cancer Institute provides access to advanced research technologies and operates within a Harvard Medical School-affiliated clinical and research community.

Funding details

Full-time permanent postdoctoral position with a listed salary of $72,000–$76,385.

What's required

Applicants must hold a PhD or MD in Molecular Biology, Cell Biology, Biochemistry, Genetics, or a related field. A strong background in DNA repair, cancer biology, or chromatin biology is preferred. Experience with mammalian cell culture, protein purification, and molecular cloning is required. Excellent communication skills, the ability to work independently and collaboratively, and a demonstrated ability to publish in peer-reviewed journals are expected.

How to apply

Apply through the external application page linked in the job listing. Review the position details and submit the requested application materials through the employer or redirected application portal.

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