Duke-NUS
2 weeks ago
Postdoctoral Research Fellow in Immunology and Inflammatory Microproteins Duke-NUS in Singapore
Degree Level
Postdoc
Field of study
Inflammation
Funding
Competitive salary plus benefits, commensurate with experience and qualifications.
Deadline
Dec 23, 2026
Country
Singapore
University
Duke-NUS

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About this position
Postdoctoral Research Fellow opportunity at Duke-NUS in Singapore focused on immunology, inflammation, systems immunology, and the emerging biology of microproteins. The Ho Lab is seeking an outstanding researcher to discover and mechanistically characterize microproteins that regulate intercellular communication and immune responses.
The project combines basic, computational, and clinical research to study how novel microproteins influence immune-cell activation, cytokine networks, and resolution of inflammation. The role includes work with primary immune-cell models, single-cell omics, proteomics, CRISPR screening, and human disease systems, with the goal of generating high-impact discoveries and potentially translating findings toward therapies for inflammatory and autoimmune disease.
Responsibilities include designing mechanistic studies, developing immune assays, translating large-scale datasets into testable hypotheses, collaborating with clinical and computational partners, prioritizing candidate microproteins, and contributing to manuscripts and reports. The position is well suited to someone who wants to build an independent scientific profile in a highly collaborative environment.
Applicants should have a PhD in Immunology or Computational Biology with a systems immunology focus, strong knowledge of adaptive and/or innate immune mechanisms, hands-on experience with primary immune cells and functional assays, and a strong publication or preprint record. Experience with chronic inflammation, autoimmunity, organoid or animal models, advanced immune phenotyping, extracellular proteins/receptors, ligand-receptor studies, or immunology drug development is desirable.
Salary is listed as competitive plus benefits, commensurate with experience and qualifications. To apply, send a CV and statement of research purpose to [email protected]. The closing date is 23 Dec 2026.
Funding details
Competitive salary plus benefits, commensurate with experience and qualifications.
What's required
PhD in Immunology or Computational Biology with a focus on systems immunology; strong foundation in molecular mechanisms of adaptive and/or innate immunity; hands-on experience with primary immune cells and immune functional assays such as cytokine profiling, immune activation assays, or immune cell phenotyping; proficiency in core molecular and cell biology techniques; track record of productivity shown by publications or preprints in immunology, inflammation, or related areas; ability to analyze and interpret complex datasets with computational colleagues; excellent communication and collaborative skills. Desirable experience includes immune signalling, chronic inflammation, autoimmunity, fibrotic complications, organoid or animal models of chronic inflammation, advanced immune phenotyping, extracellular proteins/receptors, ligand-receptor elucidation, and immunology drug development.
How to apply
Send a CV and a statement of research purpose to [email protected]. Use the Nature Careers application page if applying through the portal.
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