Postdoctoral Research Fellow in Molecular Mechanisms of Eukaryotic Transcription at the University of Sussex University of Sussex in United Kingdom

PhD opportunity at the University of Dundee in the area of cell biology , biochemistry , biophysics , genetics , and molecular biology . The project, supervised by Prof Tomo Tanaka , investigates how cells achieve correct chromosome biorientation during mitosis by regulating kinetochore-microtubule interactions . The work focuses on the outer kinetochore complexes Ndc80 and Dam1 , the role of Aurora B kinase in error correction, and how mechanical tension stabilises proper chromosome segregation...

PhD opportunity in pathological protein assembly in neurodegenerative diseases at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom . The project is centered on the molecular pathology of neurodegeneration, with a focus on amyloid filament formation by disease-associated proteins such as TDP-43 , annexin A11 , and TAF15 . Two PhD project directions are described. One aims to reproduce pathological protein filament structures in vitro using protein biochemist...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences on GPCR signalling, proteostasis, receptor trafficking, and neuropsychiatric genetics . The project, supervised by Dr Adam Grieve and Prof I Collinson , investigates how disease-associated variants in G protein-coupled receptors (GPCRs) alter receptor folding, intracellular trafficking, turnover, and signalling in neuronal systems. It combines molecular biology, cell biology, biochemistry, funct...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...

Funded PhD project at the University of Warwick, based in Coventry, United Kingdom, on translational control mechanisms that pattern early embryo development . The project focuses on how maternal mRNAs are translated in early animal embryos and how this regulates embryonic axes and early lineage specification. Research will use C. elegans embryos and combine quantitative imaging , single-mRNA live imaging , CRISPR/Cas9 gene editing , and biochemical approaches to study conserved signaling pathwa...