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University of Oxford

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Postdoctoral Researcher in Bioconjugate Chemistry and Nucleic Acid Delivery at the University of Oxford University of Oxford in United Kingdom

Degree Level

Postdoc

Field of study

Molecular Biology

Funding

This is a full-time, fixed-term contract initially for one year, with the possibility of extension subject to further external funding. The post may be eligible for a Global Talent visa. Staff on work visas may receive financial assistance toward visa renewal fees, and eligible interviewees may receive interview expense reimbursement under the department's policy.

Deadline

Nov 13, 2026

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Country

United Kingdom

University

University of Oxford

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Keywords

Molecular Biology
Chemistry
Biomedical Engineering
Drug Delivery
Biology
Medical Science
Pediatrics

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About this position

The University of Oxford is recruiting a full-time Postdoctoral Researcher to join the Gupta Lab in the Department of Paediatrics at the Institute of Development and Regenerative Medicine on the Old Road Campus.

The project focuses on bioconjugate chemistry and next-generation delivery platforms for nucleic acid therapeutics. The researcher will work at the interface of chemistry, molecular biology, and translational medicine to design and synthesise chemical conjugates for nucleic acid delivery. Research activities include linker chemistry, oligonucleotide modification, and bioconjugation to peptides, lipids, polymers, antibodies, or extracellular vesicles.

The postholder will evaluate the stability, specificity, and delivery efficacy of conjugates through in vitro and in vivo studies, collaborating with chemists, molecular biologists, and clinicians. The role is based in Oxford, United Kingdom, within the University of Oxford's Medical Sciences Division and Department of Paediatrics.

Applicants must hold a PhD and demonstrate organic chemistry and molecular biology expertise. Strong experimental design, molecular biology, data analysis, communication, and research-environment skills are expected. Applications must include a CV and supporting statement with a cover letter addressing the selection criteria.

The appointment is full-time and fixed-term for one year initially, with possible extension depending on external funding. The role may be eligible for a Global Talent visa. Applications must be submitted online by 12:00 midday on 13 November 2026.

Funding details

This is a full-time, fixed-term contract initially for one year, with the possibility of extension subject to further external funding. The post may be eligible for a Global Talent visa. Staff on work visas may receive financial assistance toward visa renewal fees, and eligible interviewees may receive interview expense reimbursement under the department's policy.

What's required

Applicants must have a PhD and proven, demonstrable organic chemistry and molecular biology skills. They should be able to design and execute experiments using various molecular biology techniques, analyse data, communicate effectively verbally and in writing with staff at all levels, and operate effectively in a demanding research environment. The application requires a CV and supporting statement including a cover letter and a clear explanation of how the applicant meets each selection criterion.

How to apply

Apply online through the jobs.ac.uk application page before 12:00 midday on Friday 13 November 2026. Upload a CV and supporting statement, including a cover letter and responses to the selection criteria. Contact Dhanu Gupta for further discussion.

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