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University Hospital of Zurich

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Postdoctoral Researcher in Experimental Hematology and Functional Genomics University Hospital Zurich in Switzerland

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Fully funded for 3–4 years, with salary and employment conditions according to Swiss National Science Foundation guidelines.

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Country

Switzerland

University

University Hospital of Zurich

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Keywords

Cell Biology
Molecular Biology
Biomedical Engineering
Biology
Stem Cell Biology
Functional Genomics
Medical Science
Hematopoiesis
Leukemia

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About this position

The Boettcher Lab, led by Principal Investigator Prof. Dr. med. Steffen Boettcher, is recruiting a postdoctoral researcher for work in experimental hematology and functional genomics. The position is based in the Department of Medical Oncology and Hematology at University Hospital Zurich and the University of Zurich, within the Comprehensive Cancer Center Zurich.

The laboratory investigates molecular mechanisms underlying normal and malignant hematopoiesis, with particular emphasis on hematopoietic stem cell biology, clonal hematopoiesis, and leukemogenesis. Its research integrates molecular and cellular technologies, functional genomics, and preclinical disease models to address biologically and clinically relevant questions.

The successful researcher will lead an innovative project on the molecular mechanisms of hematopoietic stem cell dysfunction, with the long-term aim of identifying therapeutic opportunities for patients with inherited bone marrow failure. The work will involve designing and conducting experimental projects, establishing and characterizing advanced in vitro and in vivo disease models, and applying CRISPR-based genome editing and functional genomics approaches.

Additional activities include mechanistic studies using molecular and cellular techniques, analysis of complex experimental datasets, supervision and mentoring of junior researchers and students, and contributions to scientific publications and international conference presentations. The researcher will work in a collaborative international environment with access to advanced technologies, research infrastructure, and close interaction with scientists and clinician-researchers.

Funding details

Fully funded for 3–4 years, with salary and employment conditions according to Swiss National Science Foundation guidelines.

What's required

Applicants must hold a PhD in molecular biology, biomedical sciences, genetics, cancer biology, or a related discipline. A strong experimental background in molecular and cellular biology is required. Experience in genome editing, functional genomics, or stem cell biology is highly desirable; experience with preclinical models, next-generation sequencing, or high-throughput screening is advantageous. Applicants should have a publication record appropriate to their career stage, scientific curiosity, creativity, independence, excellent organizational skills, strong communication skills, and fluency in English.

How to apply

Submit a CV, publication list, short motivation letter describing your research interests and experience, and contact details for at least two referees through the online application portal.

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