Postdoctoral Researcher in Organic Synthesis CNRS in France

CNRS Research Director Anton Granzhan is recruiting for an 18-month postdoctoral position in bioorganic chemistry and chemical biology at LCBPT (CNRS – Université Paris Cité, Paris, France). The project builds on a recent discovery of small molecules that selectively bind DNA three-way junctions and show toxicity against certain cancer cells. The next stage is to design a new generation of macrocyclic TWJ ligands and heterobifunctional probes to investigate how these molecules act in cells. Suit...

This postdoctoral project sits at the interface of organic synthesis and chemical biology, with a clear biomedical orientation toward anticancer research. The recruited researcher will help develop polyazamacrocyclic compounds as ligands for non-canonical nucleic acid structures , especially DNA three-way junctions , and then functionalize these molecules for chemical-biology applications. The position involves hands-on organic synthesis and molecular characterization , together with participati...

Postdoctoral / Research Engineer opportunity at École normale supérieure Paris (ENS Paris) , France, focused on cancer cell invasion and intracellular trafficking . The project studies how cancer cells remodel the extracellular matrix and use invadopodia , organelle trafficking, and biomolecular condensates to drive invasion. The lab works in a highly collaborative environment with expertise in cell biology , cell biophysics , and synthetic biology , and collaborates with leading institutes incl...

3-year PhD position in Biochemistry in Lyon, France , at the Molecular Microbiology and Structural Biochemistry (MMSB) Unit , CNRS / Université Lyon. The project focuses on the molecular mechanism of a multidrug efflux pump belonging to the ABC transporter superfamily . The research will combine biochemistry , structural biology , and biophysics to understand how this membrane protein recognizes and transports different substrates, with the broader goal of uncovering the molecular mechanisms und...

New postdoctoral position in Paris on molecular dynamics simulations and GPCR mechanosensitivity , hosted by the Laboratoire de Biochimie Théorique (CNRS, IBPC) in collaboration with Guillaume Stirnemann’s group at École normale supérieure . The project aims at the computational study of GPCR sensitivity to membrane lateral pressure , with close interaction with experimental biochemists and biophysicists including Laurent Catoire, Ewen Lescop, and Jean-Louis Banères. This is a strong fit for can...