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CNRS

Just Landed

Postdoctoral Researcher in RNA Systems Biochemistry and Biophysics CNRS in France

Degree Level

Postdoc

Field of study

Chemistry

Funding

Available

Deadline

Nov 25, 2026

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Country

France

University

CNRS

Apply for this position

Keywords

Chemistry
Biophysics
Biology
Molecular Evolution
Recombination
Physics

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About this position

This postdoctoral position at CNRS is embedded in the PEPR Origins and the Biosystèmes Synthétiques team at the Laboratoire de Biologie Structurale de la Cellule (BIOC, UMR 7654), CNRS – École polytechnique. The project focuses on experimental RNA reaction networks that can exhibit the core features of Darwinian evolution: reproduction, variation, and selection.

The successful candidate will work on building and characterising self-replicating, autocatalytic RNA systems and on understanding how molecular composition and environmental constraints shape their behaviour. The research combines RNA biochemistry, biophysics, and quantitative analysis to investigate processes such as ligation, recombination, amplification, and information transfer within RNA networks.

A major goal of the project is to examine how compartmentalisation, dilution, cyclic environmental changes, and other physico-chemical conditions influence stability, persistence, heredity, and evolutionary dynamics. The work is positioned in an origin-of-life context, aiming to explore how prebiotic systems can acquire evolvable properties.

The position is supervised by Pr Philippe Nghe within a research environment that includes molecular biology and RNA biochemistry laboratories, fluorescence microscopy, biophysical characterisation equipment, computing resources, and access to the unit’s experimental platforms. The postdoctoral researcher will contribute to team meetings, scientific exchanges, collaborations, publications, project reports, seminars, and collective activities within the unit and the PEPR Origins network.

Funding details

Available

How to apply

Apply through the listed Choisir le service public application page. Submit the required materials via the online portal before the deadline.

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