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National Laboratory of the Rockies

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Postdoctoral Researcher in Synthetic Biology and Metabolic Engineering for C1 Bioconversion National Laboratory of the Rockies in United States

Degree Level

Postdoc

Field of study

Biology

Funding

Full-time postdoctoral employment at 40 hours per week, with an annual salary range of $76,600–$126,400. Benefits include medical, dental, and vision insurance; short-term disability insurance; pension benefits; a 403(b) employee savings plan with employer match; life and accidental death and dismemberment insurance; paid time off and sick leave; paid holidays; and possible relocation expense reimbursement subject to eligibility. Performance-, merit-, and achievement-based awards may be availabl

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Country

United States

University

National Laboratory of the Rockies

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Keywords

Biology
Systems Biology
Synthetic Biology
Genome Editing
Metabolic Engineering
Bacterial Genetics

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About this position

The National Laboratory of the Rockies (NLR) is recruiting a full-time Postdoctoral Researcher in Synthetic Biology and Metabolic Engineering for its RRES Center and Synthetic Biology and Bioconversion group in Golden, Colorado.

The project focuses on using metabolic engineering and synthetic biology to engineer a genetically amendable, non-model bacterium. The researcher will investigate aerobic conversion of single-carbon (C1) substrates into fuels and chemicals, contributing to NLR’s broader mission in energy innovation and the development of practical, scalable biotechnologies.

The research environment combines laboratory experimentation with multidisciplinary collaboration. The postdoctoral researcher will design and implement synthetic biology tools, construct plasmids, develop synthetic operons, perform genome editing, and study bacterial metabolism and genetics. Depending on the project, the work may also involve adaptive laboratory evolution, whole-genome sequencing and analysis, metabolic modeling, and systems biology datasets including proteomics, transcriptomics, metabolomics, and fluxomics.

Within the Synthetic Biology and Bioconversion group, the researcher will plan, execute, and troubleshoot experiments; work independently and safely in the laboratory; communicate findings through written and oral scientific formats; collaborate across disciplines; and contribute to peer-reviewed publications. NLR offers access to state-of-the-art facilities and research collaborations spanning industry, academia, and other national laboratories.

Funding details

Full-time postdoctoral employment at 40 hours per week, with an annual salary range of $76,600–$126,400. Benefits include medical, dental, and vision insurance; short-term disability insurance; pension benefits; a 403(b) employee savings plan with employer match; life and accidental death and dismemberment insurance; paid time off and sick leave; paid holidays; and possible relocation expense reimbursement subject to eligibility. Performance-, merit-, and achievement-based awards may be availabl

What's required

Applicants must be recent PhD graduates within the last three years and must meet educational requirements before the employment start date. Required qualifications include a strong understanding of bacterial metabolism and genetics; research experience in metabolic engineering and synthetic biology, including designing synthetic operons, constructing plasmids, and genome editing; experience developing and implementing synthetic biology tools; a strong safety record; and the ability to deliver high-quality results within aggressive timelines. Candidates should be able to work safely and independently in a laboratory, plan, execute, and troubleshoot research, collaborate across disciplines, communicate scientific results in written and oral formats, and author peer-reviewed publications. Preferred experience includes adaptive laboratory evolution, work with non-model bacteria, whole-genome sequencing and analysis, metabolic models, and systems biology datasets such as proteomics, transcriptomics, metabolomics, and fluxomics. Employment also requires the ability to obtain and maintain a federal Personal Identity Verification card, pass required background and drug screenings, meet DOE access requirements, and obtain work authorization.

How to apply

Submit an application form for this position through the Workday application portal. Include a cover letter and resume; applications are not retained for future positions.

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