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Pennsylvania State University

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Postdoctoral Scholar - Medicine The Pennsylvania State University in United States

Degree Level

Postdoc

Field of study

Physiology

Funding

Continuation depends on university need, performance, and/or availability of funding; competitive benefits package for full-time employees.

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Country

United States

University

Pennsylvania State University

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Keywords

Physiology
Molecular Biology
Biology
Vascular Biology
Translational Medicine
Medical Science
Endothelial Dysfunction
Hypertension
Sleep Apnea
ML

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About this position

The Penn State College of Medicine is offering a postdoctoral position in the Department of Medicine in Hershey, Pennsylvania within the newly established Sleep-Vascular Program led by Dr. Rami Khayat. The program investigates the pathways linking obstructive sleep apnea with hypertension and endothelial dysfunction, with a strong emphasis on how intermittent hypoxia affects human physiology and tissue responses.

The postdoctoral scholar will take a leading role in a translational project that connects patient-based cardiovascular physiology with mechanistic experiments in human tissue and endothelial cell models. The research spans molecular and physiological approaches, including studies of nitric oxide biology in human endothelial tissue, quantitative RNA measurements, immunohistochemistry, confocal imaging, HPLC-based measurements, enzymatic assays, and chemiluminescence development. The position also involves in-vivo human work such as skin biopsy techniques, endothelial reactivity measurements, echocardiography, microneurography of sympathetic nerve activity, and microdialysis.

The scholar will participate in cardiovascular physiology studies alongside a dedicated vascular physiology team and will lead ex-vivo and in-vitro experiments under intermittent hypoxia exposure. The project is part of newly NIH-funded work and also incorporates mathematical modeling and machine learning applied to tissue hypoxia models, sleep study data, and molecular markers. The role includes collaboration with a senior project manager who oversees wet-lab operations and involves interaction with patient volunteers in a clinical research environment.

Funding details

Continuation depends on university need, performance, and/or availability of funding; competitive benefits package for full-time employees.

What's required

MD or PhD completed by the start of employment in a biological sciences discipline or equivalent. A technical background is required regardless of the PhD degree. Applicants should have experience with laboratory techniques including transcription regulation, imaging, tissue-on-chip, vascular biology, oxidative biology, or hypoxia research; some experience with human research or completion of required training; experience with statistical software; proven writing ability through publications; and excellent verbal communication skills. Desired qualifications include experience in multidisciplinary collaborative research and knowledge of analysis software and machine learning techniques.

How to apply

Current Penn State employees and students should apply through Workday using the internal student/employee process. External applicants should click Apply in the Workday posting and complete the external application.

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