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Louisiana State University

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Research Associate in Prebiotic Coacervates, Polymer Chemistry, and the Origin of Life Louisiana State University in United States

Degree Level

not provided

Field of study

Chemistry

Funding

The position is a full-time research associate appointment. The project is funded by the Alfred P. Sloan Foundation. Salary details are not stated. Eligible LSU employees and dependents may receive health, life, dental, and vision insurance, retirement options, leave, paid holidays, wellness benefits, tuition exemption for qualified positions, and other benefits.

Deadline

Nov 25, 2026

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Country

United States

University

Louisiana State University

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Keywords

Chemistry
Materials Science
Catalysis
Peptide Chemistry
Polymer Chemistry
Self-assembly
Prebiotic Chemistry
Origin Of Life

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About this position

Louisiana State University is seeking a Research Associate 2 to join Professor Donghui Zhang’s laboratory in the Department of Chemistry. The project investigates the physical and chemical mechanisms that may have contributed to the emergence of life, with particular emphasis on the FoldCat hypothesis and the catalytic potential of primitive coacervates.

The researcher will help design, synthesize, and characterize random peptoid or peptide copolymers containing hydrophobic and polar monomers. The work will examine how polymer chain composition and length influence coacervate formation and stability in the presence of prebiotic molecules, as well as whether these systems can promote peptide or nucleic-acid elongation. The broader goal is to test a proposed route by which short random peptides could generate longer protein-like chains with catalytic activity and positive feedback associated with early evolutionary dynamics.

The position combines polymer chemistry, organic synthesis, biomimetic materials, prebiotic chemistry, and catalysis. Activities include evaluating HP polymer/prebiotic-molecule coacervates, applying purification and separation methods, and using structural and biophysical characterization approaches such as recycling SEC, HPLC, mass spectrometry, X-ray and light scattering, and microscopic imaging.

The LSU research team collaborates with theoretical and experimental partners, including Ken Dill at SUNY and Ronald Zuckermann at Lawrence Berkeley National Laboratory. The Research Associate will contribute to research reports, team meetings, conference presentations, publications, and collaborative project activities in a multidisciplinary origin-of-life research environment.

Funding details

The position is a full-time research associate appointment. The project is funded by the Alfred P. Sloan Foundation. Salary details are not stated. Eligible LSU employees and dependents may receive health, life, dental, and vision insurance, retirement options, leave, paid holidays, wellness benefits, tuition exemption for qualified positions, and other benefits.

What's required

A bachelor's degree in chemistry or a related field and at least one year of experience in synthesis and structural analysis of self-assembled biomimetic or bioderived polymers are required. Preferred qualifications include a PhD in polymer chemistry, organic chemistry, materials science, or a related discipline; experience with controlled polymerization, polymer fractionation and characterization, biophysical analysis, structural characterization, X-ray and light scattering, and microscopic imaging. Applicants must submit a CV, research-experience summary, three representative publication reprints, at least two references, and a transcript if available. Original transcripts are required before hire, and candidates must have valid U.S. work authorization at hire and throughout employment.

How to apply

Apply through the LSU Careers posting. Upload a CV, research-experience summary, three representative publication reprints, at least two references, and a transcript if available. Contact Professor Donghui Zhang at [email protected] with position questions.

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