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Ute Jungwirth

5 days ago

Research Associate (Postdoctoral) in Cancer Drug Discovery and Target Validation Newcastle University in United Kingdom

Degree Level

Postdoc

Field of study

Biology

Funding

The position is part of an 18-month Cancer Research UK-funded project. It starts in January 2027 and is fixed-term until June 2028, with scope to extend. No salary or stipend amount is stated.

Deadline

Nov 20, 2026

Country flag

Country

United Kingdom

University

Newcastle University

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Keywords

Biology
Rna Biology
Medical Science
Pharmacy

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About this position

Newcastle University’s Drug Discovery Group is recruiting a postdoctoral Research Associate to join Ute Jungwirth’s team within the Newcastle University Drug Discovery Group and Cancer Research Horizons Therapeutic Innovation environment.

The 18-month Cancer Research UK-funded project will validate emerging drug targets in squamous cancers. The work centres on understanding cancer cell signalling and generating the mechanistic and phenotypic evidence needed to assess whether potential targets can support future drug discovery decisions.

The successful researcher will use genetic manipulation approaches, including RNA interference, CRISPR and inducible degron systems, alongside cell-based and molecular assays. The role requires careful experimental judgement, critical interpretation of data and the ability to design robust assays that address both mechanism and phenotype.

The researcher will work in a multidisciplinary drug discovery team and collaborate with external partners. The project offers an environment connecting cancer biology, target validation and translational drug discovery, with prior experience in target validation—particularly in a drug discovery setting—providing a useful advantage.

Funding details

The position is part of an 18-month Cancer Research UK-funded project. It starts in January 2027 and is fixed-term until June 2028, with scope to extend. No salary or stipend amount is stated.

What's required

Applicants should have a strong background in cancer cell signalling and the experimental judgement to critically interpret data. Hands-on experience with genetic manipulation techniques, including RNAi, CRISPR, and inducible degron systems, is required. Applicants should be confident designing mechanistic and phenotypic assays, interested in how target validation informs drug discovery decisions, and enthusiastic about multidisciplinary teamwork with external collaborators. Previous target-validation experience, ideally in a drug discovery setting, is advantageous.

How to apply

Apply through the Newcastle University Research Assistant/Associate vacancy linked in the post. Review the vacancy details and submit the required application before 20 November 2026.

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Professors

Principal Investigator and Senior Lecturer/Associate Professor

University Name
Country flag

United Kingdom

Research Interests

Tissue Engineering

Pharmacology

Tumor Microenvironment

Transdermal Drug Delivery

Cancer Biology