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University of British Columbia
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Research Associate - Pouladi Lab University of British Columbia in Canada
Degree Level
Postdoc
Field of study
Molecular Biology
Funding
Expected pay range: CAD 76,128 to CAD 90,000 per annum.
Deadline
Dec 13, 2026
Country
Canada
University
University of British Columbia
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About this position
The Department of Medical Genetics at the University of British Columbia is recruiting a fixed-term full-time Research Associate for the Pouladi Lab, reporting to Dr. Mahmoud Pouladi. The role is centered on research into genetic neurological disorders, with a strong emphasis on building and studying disease models that connect mouse neuroscience, stem cell biology, and translational therapeutic work.
The successful candidate will contribute to the development and analysis of novel mouse and human pluripotent stem cell models of neurological disease. The position involves investigating brain development defects in mouse models, carrying out preclinical therapeutic studies, and using complementary experimental systems to understand disease pathophysiology.
Work in the lab includes extensive hands-on research across several platforms:
- Mouse neuroscience and phenotyping — behavioral experiments, microinjection, tissue collection, sectioning, staining, and management of mouse lines.
- Histology and anatomical analysis — immunofluorescence, immunohistochemistry, ISH labeling, TEM, Golgi staining, dye tracing, 3D tissue clearing, and imaging.
- Stem cell and culture systems — differentiation of human pluripotent stem cells into neural cell types and organoids, as well as maintenance and analysis of cell line, brain slice, and primary neuron cultures.
- Molecular and genome-editing approaches — CRISPR-Cas9 editing, lentiviral shRNA work, transfection, and gene regulation experiments.
- Electrophysiology — including multi-electrode array recording.
The post sits within UBC’s Faculty of Medicine, in a department that presents itself as a productive community of scholars and a strong contributor to advances in genetic medicine. The broader research environment emphasizes innovation, technical expertise, and collaborative work across health and life sciences.
The position is located at the University of British Columbia in Vancouver, Canada.
Funding details
Expected pay range: CAD 76,128 to CAD 90,000 per annum.
What's required
Applicants should hold an MD/PhD in Anatomy, Histology, or Pathology with a focus on neurobiology and have 5+ years of postdoctoral experience. The advert also asks for at least 10 years of laboratory research experience involving mouse models, plus expertise in histology, animal husbandry, molecular biology, ex vivo/in vitro culture, human pluripotent stem cells and neural differentiation, and CRISPR/Cas9 genome editing in immortalized and human pluripotent stem cell lines.
How to apply
Send a letter of application describing your research interests and experience, a detailed CV, and the names of three referees. Submit the application through the Workday link provided in the advert.
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Prepare your application
Review drafts and confirm requirements with the university.
Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.