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The University of British Columbia

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Research Associate in Genetic Neurological Disorders and Neurobiology The University of British Columbia in Canada

Degree Level

not provided

Field of study

Biology

Funding

Full-time employment with an expected annual pay range of $76,128–$90,000. The appointment is fixed-term through March 31, 2028.

Deadline

Dec 12, 2026

Country flag

Country

Canada

University

The University of British Columbia

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Keywords

Biology
Electrophysiology
Histology
Neuropsychology
Medical Science
Neurodevelopment
Mouse Model

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About this position

The Pouladi Laboratory in the Department of Medical Genetics at The University of British Columbia is seeking a full-time Research Associate at the UBC Hospital Site in Vancouver. Reporting to Dr. Mahmoud Pouladi, the researcher will investigate the biology and treatment of genetic neurological disorders using complementary mouse and human pluripotent stem cell models.

The project will involve developing and analyzing novel disease models, examining brain-development defects, and conducting preclinical therapeutic studies. The researcher will work with mouse lines and perform or supervise behavioral experiments, tissue collection, microinjection, sectioning, staining, and other anatomical analyses. Human pluripotent stem cells will be differentiated into neural cell types and organoids, alongside work with primary neurons, brain slices, and established cell lines.

The laboratory uses a broad neurobiology toolkit, including immunofluorescence, immunohistochemistry, in situ hybridization, transmission electron microscopy, Golgi staining, dye tracing, whole-brain clearing and imaging, Western blotting, PCR, quantitative PCR, molecular cloning, Co-IP, ChIP/CLIP, lentiviral infection, transfection, and CRISPR/Cas9 genome editing. Additional research includes electrophysiological recording using multi-electrode arrays.

This role is embedded in UBC’s Department of Medical Genetics and Faculty of Medicine, a research environment spanning basic science, clinical research, and health and life sciences. The position offers an opportunity to contribute to mechanistic studies of neurological disease and the development of experimental therapeutic approaches across animal and human cellular systems.

Funding details

Full-time employment with an expected annual pay range of $76,128–$90,000. The appointment is fixed-term through March 31, 2028.

What's required

Applicants must hold an MD/PhD in Anatomy, Histology, or Pathology with a focus on neurobiology and have more than five years of postdoctoral experience. Applicants should have at least ten years of laboratory research experience involving mouse models, with expertise in histology, animal husbandry and nervous-system procedures, molecular biology, ex vivo and in vitro cell culture, human pluripotent stem cells and neural differentiation, and CRISPR/Cas9 genome editing in immortalized and human pluripotent stem cell lines. The application must include a letter outlining research interests and experience, a detailed curriculum vitae, and the names of three referees. Canadians and permanent residents of Canada will be given priority.

How to apply

Apply through the UBC Workday job portal using the direct application link. Submit a letter describing your research interests and experience, a detailed CV, and the names of three referees. A full job description may be requested from [email protected].

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