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University of North Carolina at Chapel Hill

Role of gene-environment interactions with air pollution in respiratory disease The University of North Carolina at Chapel Hill in United States

Degree Level

Postdoc

Field of study

Environmental Science

Funding

Full funding available

Deadline

Oct 14, 2026

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Country

United States

University

University of North Carolina at Chapel Hill

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Keywords

Environmental Science
Biology
Toxicology
Gene Expression
Health Science
Respiratory Medicine
Chromatin Biology
Air Pollution
Ecological Genetics
Epigenetic
Quantitative Trait Loci (qtl) Mapping
Mouse Model
Genomic
Bioinformatic
Respiratory Diseases

About this position


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Posted: Unknown

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Summary:

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Details

Posted: 14-Oct-25

Location: Chapel Hill, North Carolina


Internal Number: 307952


Vacancy ID: PDS004674

Position Summary/Description:


The Kelada Lab is seeking a post-doctoral research associate to join their research program on the role of gene-environment interactions with air pollution in respiratory disease. We seek to uncover mechanistic links between the genome (e.g., DNA sequence variants), epigenome (chromatin accessibility), gene expression, and air pollutant-induced airway inflammation phenotypes in a mouse model system. More specifically, our project will leverage genetically diverse mice from the Collaborative Cross mouse genetics reference population to identify quantitative trait loci ( QTL ) that influence response to the air pollutant ozone. In addition to QTL mapping of ozone response phenotypes, we will also analyze gene expression and chromatin accessibility in key cell types and identify expression and accessibility QTL that mediate the relationships between ozone exposure and response.
We are looking for an enthusiastic post-doctoral research associate to join this project and help lead efforts to generate and analyze these datasets. The post-doctoral research associate will have the opportunity to learn from lab members and other members of the genetics, pulmonary, and toxicology research communities at UNC , which are exceptionally strong. The post-doctoral research associate will also have the opportunity to work with a strong bioinformatics team at UNC to analyze genomic data, and the research project and environment will provide ample opportunities for training in these approaches. In addition to research, the post-doctoral research associate will be actively involved with writing scientific papers and presenting talks at scientific meetings.

Education and Experience:


Experience with mouse models of human disease
Experience with flow cytometry
Candidates should be self-motivated, enthusiastic, able to work in a teamwork environment, and have strong communication skills.


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About The University of North Carolina at Chapel Hill
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.
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Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

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