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Abinaya Chandrasekaran

Assistant Professor

University of Copenhagen

Denmark

Has grant

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Research Interests

Cell Biology

30%

Tissue Engineering

30%

Metabolic Biology

30%

Glia

30%

Autophagy

30%

Gene Therapy

20%

Oxidative Stress

20%

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Recent Grants

Grant: Close

RhoA links with Alzheimers Diseases

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

CACNA1A role in Epilepsy

Open Date: 2022-01-01

Close Date: 2022-01-01

Articles10

Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

Article Link

Year:

2024

Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

Article Link

Year:

2024

Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

Article Link

Year:

2024

Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.

Article Link

Year:

2023

Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.

Article Link

Year:

2023

Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

Article Link

Year:

2023

Charting the Explicit Path: Translational Dynamics of Hepatic Bioengineering from Experimental Benchmarks to Practical Bedside Applications

Article Link

Year:

2023

Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog.

Article Link

Year:

2021

Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.

Article Link

Year:

2021

Glutamate-Glutamine Homeostasis is Perturbed in Neurons and Astrocytes derived from Patient iPSC Models of Frontotemporal Dementia

Article Link

Year:

2020

Collaborators11

Jan Gorodkin

Professor

University of Copenhagen

DENMARK

Charlotte Brasch Andersen

Asso. professor

University of Southern Denmark

DENMARK

Mathew Blurton-Jones

Professor

University of California, Irvine

UNITED STATES

Ernst Stefan Seemann

Københavns Universitet

DENMARK

Hans H. Wandall

University of Copenhagen

DENMARK

Nadezhda T. Doncheva

Københavns Universitet

DENMARK

Giulia Ilaria Corsi

Københavns Universitet

DENMARK

Kristine Freude

Associate Professor

University of Copenhagen

DENMARK

Henriette Reventlow Frederiksen

University of Copenhagen

DENMARK

Mette Berendt

Københavns Universitet

DENMARK

Noortje de Haan

Københavns Universitet

DENMARK

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