Adachi Koichiro

Assistant Professor

Showa Pharmaceutical University

Japan

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Articles (14)

Year:

2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2021

Year:

2020

Collaborators (3)

Yoichi Tanaka

National Institute of Health Sciences

JAPAN

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Makiko Shimizu

Showa Pharmaceutical University

JAPAN

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Hiroshi Yamazaki

Showa Pharmaceutical University

JAPAN

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Adachi Koichiro

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Articles (14)

Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database

Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C9*3 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database.

Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman

Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated <i>in silico</i> as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances

A decreasing plasma concentration of a toxicologically active metabolite 9-carboxymethoxymethylguanine after dialysis – A potential new clinical biomarker for improving encephalopathy in patients treated with acyclovir

High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database

Plasma and Hepatic Exposures of Celecoxib and Diclofenac Prescribed Alone in Patients with Cytochrome P450 2C9*3 Modeled after Virtual Oral Administrations and Likely Associated with Adverse Drug Events Reported in a Japanese Database.

Updated in Silico Prediction Methods for Fractions Absorbed and Key Input Parameters of 355 Disparate Chemicals for Physiologically Based Pharmacokinetic Models for Time-Dependent Plasma Concentrations after Virtual Oral Doses in Humans.

Updated in silico prediction methods for fractions absorbed and absorption rate constants of 372 disparate chemicals for use in physiologically based pharmacokinetic models for estimating internal concentrations in rats.

Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital

Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital

Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital

Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital

Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

Collaborators (3)

Yoichi Tanaka

Makiko Shimizu

Hiroshi Yamazaki

Make your next move.

Adachi Koichiro

Research Interests

Explore related searches

Contact this professor

Articles (14)

Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database

Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C9*3 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database.

Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman

Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated &lt;i&gt;in silico&lt;/i&gt; as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances

A decreasing plasma concentration of a toxicologically active metabolite 9-carboxymethoxymethylguanine after dialysis – A potential new clinical biomarker for improving encephalopathy in patients treated with acyclovir

High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database

Plasma and Hepatic Exposures of Celecoxib and Diclofenac Prescribed Alone in Patients with Cytochrome P450 2C9*3 Modeled after Virtual Oral Administrations and Likely Associated with Adverse Drug Events Reported in a Japanese Database.

Updated in Silico Prediction Methods for Fractions Absorbed and Key Input Parameters of 355 Disparate Chemicals for Physiologically Based Pharmacokinetic Models for Time-Dependent Plasma Concentrations after Virtual Oral Doses in Humans.

Updated in silico prediction methods for fractions absorbed and absorption rate constants of 372 disparate chemicals for use in physiologically based pharmacokinetic models for estimating internal concentrations in rats.

Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital

Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital

Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital

Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital

Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

Collaborators (3)

Yoichi Tanaka

Makiko Shimizu

Hiroshi Yamazaki

Make your next move.

Octanol/water partition coefficients estimated using retention times in reverse-phase liquid chromatography and calculated <i>in silico</i> as one of the determinant factors for pharmacokinetic parameter estimations of general chemical substances