Adam Skarka

University of Hradec Kralove, Faculty of Science

Czech Republic

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Articles (8)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (9)

Marketa Chvojkova

National Institute of Mental Health

CZECH REPUBLIC

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Kristina Holubova

National Institute of Mental Health

CZECH REPUBLIC

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Alžběta Dlabková

CZECH REPUBLIC

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Monika Schmidt

Assistant professor

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Zofia Chrienova

University of Hradec Králové

CZECH REPUBLIC

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David Malinak

Assistant Professor

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Jaroslav Pejchal

Chief of toxicology group/associate professor

CZECH REPUBLIC

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Eva Petrlíková Eva Novotná

Charles University in Prague

CZECH REPUBLIC

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Jakub Hofman

academic research and teaching fellow

Faculty of Pharmacy, Charles University

CZECH REPUBLIC

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Adam Skarka

Research Interests

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Articles (8)

Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents

7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication

BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS

Frentizole derivatives with mTOR inhibiting and senomorphic properties

Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

Silencing of E-cadherin expression leads to increased chemosensitivity to irinotecan and oxaliplatin in colorectal cancer cell lines

Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme

Collaborators (9)

Marketa Chvojkova

Kristina Holubova

Alžběta Dlabková

Monika Schmidt

Zofia Chrienova

David Malinak

Jaroslav Pejchal

Eva Petrlíková Eva Novotná

Jakub Hofman

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