Adil Mardinoglu

Professor

King’s College London

United Kingdom

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About

Professor Adil Mardinoglu is a faculty member at King's College London, United Kingdom. His research focuses on systems biology, particularly in understanding sarcopenia, chronic liver diseases, and cancer through innovative approaches including proteomics and metabolomics. His recent publications explore the complexities of big biological data in the AI era and the development of targeted therapies for various cancers.

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Collaborators (14)

Marja-Riitta Taskinen

University of Helsinki

FINLAND

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Mikael Åberg

Associate professor

Uppsala University

SWEDEN

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Mathias Uhlen

Professor

SWEDEN

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Adnane Achour

Professor

Karolinska Institutet

SWEDEN

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María Bueno Álvez

KTH Royal Institute of Technology

SWEDEN

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Jan Borén

Professor

University of Gothenburg

SWEDEN

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Tobias Sjöblom

Professor at Uppsala University

Uppsala University

SWEDEN

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Soham Gupta

Karolinska Institutet

SWEDEN

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Håkan Brorson

Department of Clinical Sciences, Lund University

SWEDEN

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Tiphaine Le Roy

FRANCE

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Karine Clément

Sorbonne Université

FRANCE

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Morten Grøtli

Professor

University of Gothenburg

SWEDEN

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Cheng Zhang

KTH Royal Institute of Technology

SWEDEN

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Riikka Kivelä

University of Helsinki

FINLAND

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Adil Mardinoglu

Research Interests

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About

Articles (28)

Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach

Longitudinal big biological data in the AI era

Systematically identification of survival-associated eQTLs in a Japanese kidney cancer cohort

Synthesis and biological assessment of BUB1B inhibitors for the treatment of clear cell renal cell carcinoma

Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(<i>1H</i>)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme

Advancing Chronic Liver Disease Diagnoses: Targeted Proteomics for the Non-Invasive Detection of Fibrosis

Noscapine-bile acid hybrids as novel anticancer agents

Genome-scale models in human metabologenomics

Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach

Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins

High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348

Drug repositioning for immunotherapy in breast cancer using single-cell analysis

Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

Multi‐omics characterization of lymphedema‐induced adipose tissue resulting from breast cancer‐related surgery

Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention

Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients

Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection

Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds

Next generation pan-cancer blood proteome profiling using proximity extension assay

Drug repositioning targeting glutaminase reveals drug candidates for the treatment of Alzheimer’s disease patients

Revisiting the role of serine metabolism in hepatic lipogenesis

Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma

Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase

Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson’s Disease Model

Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.

Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells

Synthesis, Characterization, Theoretical Studies and in Vitro Embriyotoxic, Genotoxic and Anticancer Effects of Novel Phenyl(1,4,6-Triphenyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidin-5-yl)Methanone

Collaborators (14)

Marja-Riitta Taskinen

Mikael Åberg

Mathias Uhlen

Adnane Achour

María Bueno Álvez

Jan Borén

Tobias Sjöblom

Soham Gupta

Håkan Brorson

Tiphaine Le Roy

Karine Clément

Morten Grøtli

Cheng Zhang

Riikka Kivelä

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