Jan Borén

Professor

University of Gothenburg

Sweden

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About

Jan Borén is a Professor at the University of Gothenburg in Sweden. His research focuses on cardiovascular health, particularly the roles of lipoproteins and metabolic pathways in heart disease and arrhythmias. Recent publications include studies on ceramide synthase, apolipoprotein B, and targeted therapies for liver diseases. He advocates for improved testing and management of lipoprotein(a) levels in clinical practice.

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2022

Collaborators (17)

Elmir Omerovic

Karolinska University Hospital

SWEDEN

Jan Borén

Research Interests

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About

Articles (20)

Ceramide Synthase 2 Promotes Cardiac Very-Long-Chain Dihydroceramide Accumulation and Is Linked to Arrhythmias and Heart Failure in Humans

Editorial: The Brussels International Declaration on Lp(a) Testing And Management—A call to action

The test that pays for itself: Why we can no longer afford to ignore Lp(a)

Apolipoprotein B-containing lipoproteins in atherogenesis

Genetically determined increase in apolipoprotein C-III (APOC3 gain-of-function) delays very low-density lipoprotein clearance in humans

Targeting PKLR in liver diseases

Plasma Triglyceride Reduction and Cardiovascular Risk in ODYSSEY Outcomes Trial

Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

Quantifying Triglyceride-Rich Lipoprotein Atherogenicity, Associations With Inflammation, and Implications for Risk Assessment Using Non-HDL Cholesterol

Role of Perilipins in Oxidative Stress—Implications for Cardiovascular Disease

Revisiting the role of serine metabolism in hepatic lipogenesis

Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase

Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study

Twenty Years of Cardiovascular Complications and Risk Factors in Patients With Type 2 Diabetes: A Nationwide Swedish Cohort Study

Replacing Foods with a High-Glycemic Index and High in Saturated Fat by Alternatives with a Low Glycemic Index and Low Saturated Fat Reduces Hepatic Fat, Even in Isocaloric and Macronutrient Matched Conditions

Cover Feature: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase (ChemBioChem 1/2023)

Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia

Left-Sided Degenerative Valvular Heart Disease in Type 1 and Type 2 Diabetes

Collaborators (17)

Elmir Omerovic

Christoph J. Binder

Marja-Riitta Taskinen

Annika Rosengren

Mathias Uhlen

Adil Mardinoglu

Amalyn Nain-Perez

Ulf Smith

Hertzel C. Gerstein

Chris J Packard

Göran Bergström

Darren McGuire

John J V McMurray

Malin Levin

Björn Eliasson

Morten Grøtli

Cheng Zhang

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